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Formyl Peptide Receptor-Like 1 (FPR2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619362

MBS619362 is an antibody targeting FPR2. Also known as Formyl Peptide Receptor-like 1 (FPRL1, Formyl Peptide Receptor 2, FPR2, FMLP R I, FMLP R II, FMLP-related Receptor I, FMLPX, FPR2A, FPRH1, FPRH2, HM63, Lipoxin A4 Receptor, LXA4 Receptor, LXA4R, RFP).… More details

$940 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Formyl Peptide Receptor-like 1 (FPR2), Polyclonal Antibody
Full Product Name
Formyl Peptide Receptor-like 1 (FPRL1, Formyl Peptide Receptor 2, FPR2, FMLP R I, FMLP R II, FMLP-related Receptor I, FMLPX, FPR2A, FPRH1, FPRH2, HM63, Lipoxin A4 Receptor, LXA4 Receptor, LXA4R, RFP)
Product Gene Name
anti-FPR2 antibody
Product Synonym Names
Anti -Formyl Peptide Receptor-like 1 (FPRL1, Formyl Peptide Receptor 2, FPR2, FMLP R I, FMLP R II, FMLP-related Receptor I, FMLPX, FPR2A, FPRH1, FPRH2, HM63, Lipoxin A4 Receptor, LXA4 Receptor, LXA4R, RFP)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with 100ul sterile ddH2O.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Formyl Peptide Receptor-like 1 (FPRL1).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
38,964 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (52264453..52273779). Location: 19q13.3-q13.4
OMIM
136538
3D Structure
ModBase 3D Structure for P25090
Immunogen
Synthetic peptide corresponding to the C-terminal of human FPRL1 (KLH).
Positive Control
HL-60

Product Categories/Family for anti-FPR2 antibody

Antibodies; Abs to Receptors
Applications Tested/Suitable for anti-FPR2 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-FPR2 antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 1:600
Western Blot: 1:6000

Western Blot (WB) of anti-FPR2 antibody

Western Blot analysis of extracts from HL-60 cells using MBS619362. Band at ~38kD.
Rabbit Anti-FPR2 Polyclonal Antibody – Cat# MBS619362

Immunofluorescence (IF) of anti-FPR2 antibody

Immunofluorescent analysis of HL-60 cells using MBS619362 (green). Nuclei have been labeled with Pi (red).
Rabbit Anti-FPR2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS619362

Other Notes

Small volumes of anti-FPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FPR2. It may not necessarily be applicable to this product.

NCBI GI #
29293107
NCBI GeneID
2358
UniProt Primary Accession #
P25090
UniProt Secondary Accession #
A8K3E2
UniProt Related Accession #
P25090; AAB23104
NCBI Official Full Name
formyl peptide receptor-like 1
NCBI Official Synonym Full Names
formyl peptide receptor 2
NCBI Official Symbol
FPR2
NCBI Official Synonym Symbols
ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
UniProt Protein Name
N-formyl peptide receptor 2
UniProt Synonym Protein Names
FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
Protein Family
Formyl peptide receptor
UniProt Gene Name
FPR2
UniProt Synonym Gene Names
FPRH1; FPRL1; LXA4R
UniProt Entry Name
FPR2_HUMAN
NCBI Protein Information
N-formyl peptide receptor 2; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related)

UniProt Comments for FPR2

FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; inflammatory response; cell adhesion; chemotaxis; cell motility
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Research Articles on FPR2

1. the innate immune system may be able to respond in different ways to pathogenic or innocuous staphylococci by monitoring the presence of phenol-soluble modulins via FPR2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FPR2 antibody

 Reference Product  PubMed Publications
 CAMP antibody  >9 publications with FPR2 and CAMP

Pathways associated with anti-FPR2 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram

Diseases associated with anti-FPR2 antibody

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >22 publications with FPR2 and Immune System Diseases
 Neoplasms Antibodies  >17 publications with FPR2 and Neoplasms
 Neurodegenerative Diseases Antibodies  >12 publications with FPR2 and Neurodegenerative Diseases
 Pain Antibodies  >12 publications with FPR2 and Pain
 Autoimmune Diseases Antibodies  >11 publications with FPR2 and Autoimmune Diseases
 Vascular Diseases Antibodies  >10 publications with FPR2 and Vascular Diseases
 Skin Diseases Antibodies  >8 publications with FPR2 and Skin Diseases
 Cardiovascular Diseases Antibodies  >8 publications with FPR2 and Cardiovascular Diseases
 Leukemia Antibodies  >7 publications with FPR2 and Leukemia
 Glioma Antibodies  >7 publications with FPR2 and Glioma

Organs/Tissues associated with anti-FPR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >133 publications with FPR2 and Blood
 Lung Antibodies  >24 publications with FPR2 and Lung
 Kidney Antibodies  >13 publications with FPR2 and Kidney
 Connective Tissue Antibodies  >5 publications with FPR2 and Connective Tissue
 Bone Marrow Antibodies  >4 publications with FPR2 and Bone Marrow
 Spleen Antibodies  >4 publications with FPR2 and Spleen
 Heart Antibodies  >2 publications with FPR2 and Heart
 Testis Antibodies  >1 publications with FPR2 and Testis
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