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Osteoactivin (GPNMB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619689

MBS619689 is an antibody targeting Gpnmb. Also known as Osteoactivin (Glycoprotein (transmembrane) nmb, Gpnmb, Dchil, DC-HIL, Dendritic cell-associated transmembrane protein, ipd, Nmb, Osteoactivin, Transmembrane glycoprotein NMB). Reactive in Rat. Host:… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Osteoactivin (Gpnmb), Polyclonal Antibody
Full Product Name
Osteoactivin (Glycoprotein (transmembrane) nmb, Gpnmb, Dchil, DC-HIL, Dendritic cell-associated transmembrane protein, ipd, Nmb, Osteoactivin, Transmembrane glycoprotein NMB)
Product Gene Name
Product Synonym Names
Anti -Osteoactivin (Glycoprotein (transmembrane) nmb, Gpnmb, Dchil, DC-HIL, Dendritic cell-associated transmembrane protein, ipd, Nmb, Osteoactivin, Transmembrane glycoprotein NMB)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute in ddH2O.
Purity/Purification
Serum
Serum
Specificity
Recognizes rat Osteoactivin (aa 551-568)
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
63,731 Da
Chromosome Location
chromosome: 4; Location: 4q24
3D Structure
ModBase 3D Structure for Q6P7C7
Immunogen
Synthetic rat osteoactivin peptide (aa551-568) (KAPFSRGDREKDPLLQDK)

Product Categories/Family for anti-Gpnmb antibody

Applications Tested/Suitable for anti-Gpnmb antibody
ELISA (EL/EIA)
Application Notes for anti-Gpnmb antibody
Suitable for use in ELISA.
Dilution: ELISA: 1:5000

Other Notes

Small volumes of anti-Gpnmb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Gpnmb. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
osteoactivin
NCBI Official Synonym Full Names
glycoprotein (transmembrane) nmb
NCBI Official Symbol
Gpnmb
NCBI Official Synonym Symbols
Gpnmb
UniProt Protein Name
Transmembrane glycoprotein NMB
UniProt Gene Name
Gpnmb
UniProt Entry Name
GPNMB_RAT
NCBI Protein Information
transmembrane glycoprotein NMB; osteoactivin

NCBI Summary for Gpnmb

may play a role in bone matrix production and mineralization; overexpressed in the osteopetrosis mutant op rat [RGD]

UniProt Comments for Gpnmb

Function: Could be a melanogenic enzyme

Subcellular location: Membrane; Single-pass type I membrane protein

Potential. Melanosome

Sequence similarities: Belongs to the PMEL/NMB family.Contains 1 PKD domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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