• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Speedy-1 (SPDYA) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619771

Speedy/Ringo (Spy1) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. It mediates cell survival during the DNA damage process through activation of CDK2. More details

$775 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Speedy-1 (SPDYA), Polyclonal Antibody
Full Product Name
Speedy-1 (SPDY1, SPY1, Speedy Homolog A, SPDYA, MGC110856, MGC57218, Rapid Inducer of G2/M Progression in Oocytes A, Ringo3)
Product Gene Name
Product Synonym Names
Anti -Speedy-1 (SPDY1, SPY1, Speedy Homolog A, SPDYA, MGC110856, MGC57218, Rapid Inducer of G2/M Progression in Oocytes A, Ringo3)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Tris-citrate/phosphate (pH 7-8)
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
This antibody is specific for human Speedy/Ringo protein. Species Crossreactivity: Mouse. Other species have not been tested.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
36,463 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (29033462..29073476). Location: 2p23.2
OMIM
614029
3D Structure
ModBase 3D Structure for Q5MJ70
Immunogen
A synthetic peptide made to a C-terminal region of the human Speedy protein (within residues 200-286). This immunogen is conserved in both isoforms 1 and 2 [Swiss-Prot Q5MJ69].
Cellular Localization
Nuclear
Positive Control
Mouse testis lysate

Product Categories/Family for anti-SPDYA antibody

Applications Tested/Suitable for anti-SPDYA antibody
Western Blot (WB)
Application Notes for anti-SPDYA antibody
Suitable for use in Western Blot.

Other Notes

Small volumes of anti-SPDYA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SPDYA purchase

MBS619771 is an antibody targeting SPDYA. Also known as Speedy-1 (SPDY1, SPY1, Speedy Homolog A, SPDYA, MGC110856, MGC57218, Rapid Inducer of G2/M Progression in Oocytes A, Ringo3). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SPDYA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
speedy protein A isoform 1
NCBI Official Synonym Full Names
speedy/RINGO cell cycle regulator family member A
NCBI Official Symbol
SPDYA
NCBI Official Synonym Symbols
SPY1; SPDY1; RINGO3; RINGOA
UniProt Protein Name
Speedy protein A
UniProt Synonym Protein Names
Rapid inducer of G2/M progression in oocytes A; RINGO A; hSpy/Ringo A; Speedy-1
Protein Family
UniProt Gene Name
SPDYA
UniProt Synonym Gene Names
SPDY1; SPY1; RINGO A; hSpy/Ringo A; Spy1
UniProt Entry Name
SPDYA_HUMAN
NCBI Protein Information
speedy protein A; RINGO A; speedy-1; hSpy/Ringo A; speedy homolog A; rapid inducer of G2/M progression in oocytes A

UniProt Comments for SPDYA

SPDYA: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2. Belongs to the Speedy/Ringo family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2p23.2

Cellular Component: nucleus

Molecular Function: protein kinase binding

Biological Process: positive regulation of cyclin-dependent protein kinase activity; multicellular organismal development; positive regulation of cell proliferation; male meiosis; response to DNA damage stimulus; G1/S transition of mitotic cell cycle
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SPDYA antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000