Rabbit Anti-FNBP1L Polyclonal Antibody – Cat# MBS619837

Western blot analysis of TOCA-1 in human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide with TOCA-1 antibody at 0.5 ug/ml.

Formin Binding Protein 1-Like (FNBP1L) Antibody – Rabbit Polyclonal

Name: FNBP1L Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS619837
Price: 850 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619837

Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein… More details

$850 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Formin Binding Protein 1-like (FNBP1L), Polyclonal Antibody

Full Product Name

Formin Binding Protein 1-like, NT (C1orf39, FLJ20275, TOCA1, Toca-1, Transducer of Cdc42-dependent actin assembly protein 1)

Product Gene Name

anti-FNBP1L antibody

Product Synonym Names

Anti -Formin Binding Protein 1-like, NT (C1orf39, FLJ20275, TOCA1, Toca-1, Transducer of Cdc42-dependent actin assembly protein 1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied as a liquid in PBS, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human TOCA-1. Species crossreactivity: Mouse and rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

69,977 Da

OMIM

608848

3D Structure

ModBase 3D Structure for Q5T0N5

Immunogen

Synthetic peptide corresponding to 15aa from near the amino terminus of the human TOCA-1 (GenBank accession no. NP_001020119).

Product Categories/Family for anti-FNBP1L antibody

Antibodies; Abs to Cell Division Cycle (CDC)

Applications Tested/Suitable for anti-FNBP1L antibody

Western Blot (WB)

Application Notes for anti-FNBP1L antibody

Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-2ug/ml

Other Notes

Small volumes of anti-FNBP1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FNBP1L purchase

MBS619837 is an antibody targeting FNBP1L. Also known as Formin Binding Protein 1-like, NT (C1orf39, FLJ20275, TOCA1, Toca-1, Transducer of Cdc42-dependent actin assembly protein 1). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FNBP1L. It may not necessarily be applicable to this product.

NCBI GI #

56205711

UniProt Primary Accession #

Q5T0N5

UniProt Secondary Accession #

Q5T0N6; Q6B097; Q6P653; Q6R4Q4; Q9NXG1

NCBI Official Full Name

formin binding protein 1-like

UniProt Protein Name

Formin-binding protein 1-like

UniProt Synonym Protein Names

Transducer of Cdc42-dependent actin assembly protein 1

Protein Family

Formin-binding protein

UniProt Gene Name

FNBP1L

UniProt Synonym Gene Names

C1orf39; TOCA1

UniProt Entry Name

FBP1L_HUMAN

UniProt Comments for FNBP1L

FNBP1L: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens. Belongs to the FNBP1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p22.1

Cellular Component: cytoskeleton; cytoplasm; cytoplasmic membrane-bound vesicle; plasma membrane; cell cortex

Molecular Function: protein binding; lipid binding

Biological Process: positive regulation of filopodium formation; vesicle transport along actin filament; vesicle organization and biogenesis; membrane invagination; autophagy; cilium biogenesis; membrane budding

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FNBP1L antibody

Reference Product	PubMed Publications
FLNA antibody	>12 publications with FNBP1L and FLNA

Pathways associated with anti-FNBP1L antibody

Products by Pathway	Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram

Diseases associated with anti-FNBP1L antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>2 publications with FNBP1L and Carcinoma
Neoplasm Invasiveness Antibodies	>2 publications with FNBP1L and Neoplasm Invasiveness
Neoplasms Antibodies	>2 publications with FNBP1L and Neoplasms
Melanoma Antibodies	>1 publications with FNBP1L and Melanoma
Breast Neoplasms Antibodies	>1 publications with FNBP1L and Breast Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with FNBP1L and Neoplasm Metastasis
Carcinoma, Small Cell Antibodies	>1 publications with FNBP1L and Carcinoma, Small Cell
Blood Coagulation Disorders Antibodies	>1 publications with FNBP1L and Blood Coagulation Disorders

Organs/Tissues associated with anti-FNBP1L antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with FNBP1L and Brain