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Collagen Type XXIII (COL23A1) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619897

Collagen XXIII 1 (COL23A1) is an epithelial cell type 2 transmembrane glycoprotein with multiple collagen-like domains in its extracellular region. Intracellular furin-mediated cleavage of the molecule generates a 58kD shed fragment that forms… More details

$1105 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Collagen Type XXIII (COL23A1), Polyclonal Antibody
Full Product Name
Collagen Type XXIII (COL23A1, alpha 1, Collagen alpha-1(XXIII) chain, DKFZp434K0621)
Product Gene Name
Product Synonym Names
Anti -Collagen Type XXIII (COL23A1, alpha 1, Collagen alpha-1(XXIII) chain, DKFZp434K0621)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with sterile PBS. If 0.5ml of PBS is used, the antibody concentration will be 0.2mg/ml.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human COL23A1 in direct ELISAs and Western blots. In these formats, this antibody shows less than 5% cross-reactivity with Recombinant, Human COL25A1.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute by adding sterile 40-50% glycerol, PBS, 0.02% sodium azide. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
51,944 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (177664617..178017556, complement). Location: 5q35.3
OMIM
610043
3D Structure
ModBase 3D Structure for Q86Y22
Immunogen
NS0-derived Recombinant, Human COL23A1 isoform 1

Product Categories/Family for anti-COL23A1 antibody

Applications Tested/Suitable for anti-COL23A1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-COL23A1 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.5-1ug/ml. The detection limit for rhCOL23A1 is approximately 0.1ng/well.
Western Blot:1ug/ml. Tissue lysates were resolved by SDS-PAGE,transferred to an Immobilon-P membrane and
immunoblotted with 1.0ug/ml sheep anti-humanCOL23A1.

SDS-Page of anti-COL23A1 antibody

Tissue lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with (1ug/ml) sheep anti-hCOL23A1.
Sheep Anti-COL23A1 Polyclonal Antibody – Cat# MBS619897

Other Notes

Small volumes of anti-COL23A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COL23A1 purchase

MBS619897 is an antibody targeting COL23A1. Also known as Collagen Type XXIII (COL23A1, alpha 1, Collagen alpha-1(XXIII) chain, DKFZp434K0621). Reactive in Human. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for COL23A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
collagen, type XXIII, alpha 1, isoform CRA_a
NCBI Official Synonym Full Names
collagen, type XXIII, alpha 1
NCBI Official Symbol
COL23A1
NCBI Official Synonym Symbols
DKFZp434K0621
UniProt Protein Name
Collagen alpha-1(XXIII) chain
Protein Family
UniProt Gene Name
COL23A1
UniProt Entry Name
CONA1_HUMAN
NCBI Protein Information
collagen alpha-1(XXIII) chain; collagen alpha-1(XXIII) chain; OTTHUMP00000161490; procollagen, type XXIII, alpha 1

NCBI Summary for COL23A1

COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM]

UniProt Comments for COL23A1

COL23A1: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: collagen; endoplasmic reticulum lumen; plasma membrane; integral to membrane

Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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