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CCDC5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6199931

CCDC5 is regulator of spindle function and integrity during the metaphase-anaphase transition. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCDC5, Monoclonal Antibody
Full Product Name
CCDC5 (HAUS Augmin-like Complex Subunit 1, Coiled-coil Domain-containing Protein 5, Enhancer Of Invasion-Cluster, HEI-C, HAUS1, HEIC, FLJ21094, FLJ40084) (MaxLight 490)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1E3
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human CCDC5.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
22,744 Da
OMIM
608775
3D Structure
ModBase 3D Structure for Q96CS2
Immunogen
Partial recombinant corresponding to aa179-279 from human CCDC5 (NP_612452) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
RQNMDFLKAKSEEFRFGIKAAEEQLSARGMDASLSHQSLVALSEKLARLKQQTIPLKKKLESYLDLMPNPSLAQVKIEEAKRELDSIEAELTRRVDMMEL
Conjugate
MaxLight490
Applications Tested/Suitable for anti-CCDC5 antibody
FLISA, Western Blot (WB)
Application Notes for anti-CCDC5 antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-CCDC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCDC5 purchase

MBS6199931 is an antibody targeting CCDC5. Also known as CCDC5 (HAUS Augmin-like Complex Subunit 1, Coiled-coil Domain-containing Protein 5, Enhancer Of Invasion-Cluster, HEI-C, HAUS1, HEIC, FLJ21094, FLJ40084) (MaxLight 490). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CCDC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
HAUS augmin-like complex subunit 1
NCBI Official Synonym Full Names
HAUS augmin-like complex, subunit 1
NCBI Official Symbol
HAUS1
NCBI Official Synonym Symbols
HEIC; CCDC5; HEI-C; HsT1461
UniProt Protein Name
HAUS augmin-like complex subunit 1
UniProt Synonym Protein Names
Coiled-coil domain-containing protein 5; Enhancer of invasion-cluster; HEI-C
UniProt Gene Name
HAUS1
UniProt Synonym Gene Names
CCDC5; HEIC; HEI-C
UniProt Entry Name
HAUS1_HUMAN
NCBI Protein Information
HAUS augmin-like complex subunit 1; coiled-coil domain containing 5 (spindle associated); coiled-coil domain-containing protein 5; enhancer of invasion-cluster

NCBI Summary for CCDC5

HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
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UniProt Comments for CCDC5

CCDC5: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS1 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: spindle pole; centrosome; microtubule; cytoplasm

Molecular Function: protein binding

Biological Process: mitosis; cell division; centrosome organization and biogenesis; spindle assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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