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CYP24A1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6200375

CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CYP24A1, Monoclonal Antibody
Full Product Name
CYP24A1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, Mitochondrial, Vitamin D(3) 24-hydroxylase, 24-OHase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24) (MaxLight 490)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1E1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human CYP24A1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
43,051 Da
OMIM
126065
3D Structure
ModBase 3D Structure for Q32ML3
Immunogen
Partial recombinant corresponding to aa415-514 from human CYP24A1 (NP_000773) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
LMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLHSGTLVPSRELPIAFCQR
Conjugate
MaxLight490

Product Categories/Family for anti-CYP24A1 antibody

Applications Tested/Suitable for anti-CYP24A1 antibody
FLISA, Western Blot (WB)
Application Notes for anti-CYP24A1 antibody
Applications are based on unconjugated antibody.

Product References and Citations for anti-CYP24A1 antibody

1. Dysregulation of renal vitamin D metabolism in the uremic rat. Helvig CF, Cuerrier D, Hosfield CM, Ireland B, Kharebov AZ, Kim JW, Ramjit NJ, Ryder K, Tabash SP, Herzenberg AM, Epps TM, Petkovich M.Kidney Int. 2010 Jun 9.

Other Notes

Small volumes of anti-CYP24A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYP24A1 purchase

MBS6200375 is an antibody targeting CYP24A1. Also known as CYP24A1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, Mitochondrial, Vitamin D(3) 24-hydroxylase, 24-OHase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24) (MaxLight 490). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CYP24A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform 1
NCBI Official Synonym Full Names
cytochrome P450, family 24, subfamily A, polypeptide 1
NCBI Official Symbol
CYP24A1
NCBI Official Synonym Symbols
CP24; HCAI; CYP24; P450-CC24
UniProt Protein Name
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
UniProt Synonym Protein Names
Cytochrome P450 24A1; Cytochrome P450-CC24
UniProt Gene Name
CYP24A1
UniProt Synonym Gene Names
CYP24; 24-OHase; Vitamin D(3) 24-hydroxylase
UniProt Entry Name
CP24A_HUMAN
NCBI Protein Information
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 1,25-@dihydroxyvitamin D3 24-hydroxylase; 24-OHase; cytochrome P450 24A1; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); cytoc

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CYP24A1 antibody

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway antibodies  Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway Diagram
 Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway antibodies  Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway Diagram
 Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway antibodies  Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway Diagram
 Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway antibodies  Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway Diagram
 Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway antibodies  Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway Diagram
 Defective CYP1B1 Causes Glaucoma Pathway antibodies  Defective CYP1B1 Causes Glaucoma Pathway Diagram
 Defective CYP21A2 Causes Adrenal Hyperplasia 3 (AH3) Pathway antibodies  Defective CYP21A2 Causes Adrenal Hyperplasia 3 (AH3) Pathway Diagram
 Defective CYP24A1 Causes Hypercalcemia, Infantile (HCAI) Pathway antibodies  Defective CYP24A1 Causes Hypercalcemia, Infantile (HCAI) Pathway Diagram
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