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Aldehyde Dehydrogenase 1a1 (ALDH1A1) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620161

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be… More details

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Product Overview

Online Datasheet in PDF
Product Name
Aldehyde Dehydrogenase 1A1 (ALDH1A1), Polyclonal Antibody
Full Product Name
Aldehyde Dehydrogenase 1A1 (Aldh1a1, Acetaldehyde Dehydrogenase 1, AHD2, ALDC, Aldehyde Dehydrogenase 1 Soluble, Aldehyde Dehydrogenase 1A1, Aldehyde Dehydrogenase Cytosolic, Aldehyde Dehydrogenase Liver (cytosolic), MGC2318, PUMB1, RALDH 1, RalDH1, Retin
Product Gene Name
Product Synonym Names
Anti -Aldehyde Dehydrogenase 1A1 (Aldh1a1, Acetaldehyde Dehydrogenase 1, AHD2, ALDC, Aldehyde Dehydrogenase 1 Soluble, Aldehyde Dehydrogenase 1A1, Aldehyde Dehydrogenase Cytosolic, Aldehyde Dehydrogenase Liver (cytosolic), MGC2318, PUMB1, RALDH 1, RalDH1, Retin
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ALDH1A1 at ~55kD in Human Liver lysates (calculated MW of 54.9kD according to NP_000680.2). Species Crossreactivity: Mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
35,780 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (75515587..75567969, complement). Location: 9q21.13
3D Structure
ModBase 3D Structure for Q59EJ0
Immunogen
Synthetic peptide corresponding to the internal region of human ALDH1A1.
Applications Tested/Suitable for anti-ALDH1A1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-ALDH1A1 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:32000
Western Blot: 1-3ug/ml

Western Blot (WB) of anti-ALDH1A1 antibody

Western blot analysis of ALDH1A1 in Human Liver Lysate (35μg protein in RIPA buffer) using ALDH1A1 antibody (1μg/ml).
Goat Anti-ALDH1A1 Polyclonal Antibody – Cat# MBS620161

Other Notes

Small volumes of anti-ALDH1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH1A1 purchase

MBS620161 is an antibody targeting ALDH1A1. Also known as Aldehyde Dehydrogenase 1A1 (Aldh1a1, Acetaldehyde Dehydrogenase 1, AHD2, ALDC, Aldehyde Dehydrogenase 1 Soluble, Aldehyde Dehydrogenase 1A1, Aldehyde Dehydrogenase Cytosolic, Aldehyde Dehydrogenase Liver (cytosolic), MGC2318, PUMB1, RALDH 1, RalDH1, Retin. Reactive in Human, Mouse, Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
aldehyde dehydrogenase 1A1 variant
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member A1
NCBI Official Symbol
ALDH1A1
NCBI Official Synonym Symbols
ALDC; ALDH1; PUMB1; ALDH11; RALDH1; ALDH-E1; MGC2318
UniProt Protein Name
Aldehyde dehydrogenase 1A1 variant
Protein Family
UniProt Entry Name
Q59EJ0_HUMAN
NCBI Protein Information
retinal dehydrogenase 1; ALHDII; RALDH 1; ALDH class 1; OTTHUMP00000021482; acetaldehyde dehydrogenase 1; retinaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic

NCBI Summary for ALDH1A1

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq]
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UniProt Comments for ALDH1A1

ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.

Protein type: Apoptosis; EC 1.2.1.36; Oxidoreductase; GAPs; Cofactor and Vitamin Metabolism - retinol; GAPs, Ras

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; 3-chloroallyl aldehyde dehydrogenase activity; benzaldehyde dehydrogenase (NAD+) activity; retinal dehydrogenase activity

Biological Process: retinol metabolic process; xenobiotic metabolic process; aldehyde metabolic process; ethanol oxidation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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