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PANX2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620195

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PANX2, Polyclonal Antibody
Full Product Name
PANX2 (Pannexin2)
Product Gene Name
Product Synonym Names
Anti -PANX2 (Pannexin2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Canine, Human, Mouse, Rat0
Form/Format
Supplied as a powder lyophilized from a solution containing PBS with 2% sucrose. Reconstitute with 50ul sterile ddH2O or sterile 40-50% glycerol for long-term storage.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PANX2. Species Crossreactivity: mouse, rat, canine and zebra fish.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
38,932 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (50609160..50618724). Location: 22q13.33
3D Structure
ModBase 3D Structure for Q495U3
Immunogen
Synthetic peptide corresponding to a region of Human PANX2
Applications Tested/Suitable for anti-PANX2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PANX2 antibody
Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Dilution: ELISA: 1:60,000 (titer)
Immunohistochemistry (paraffin): 4-8ug/ml
Western Blot: 1.25ug/ml
Optimal dilution to be determined by the researcher.

Other Notes

Small volumes of anti-PANX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PANX2 purchase

MBS620195 is an antibody targeting PANX2. Also known as PANX2 (Pannexin2). Reactive in Canine, Human, Mouse, Rat0. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PANX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pannexin-2 isoform 2
NCBI Official Synonym Full Names
pannexin 2
NCBI Official Symbol
PANX2
NCBI Official Synonym Symbols
PX2; hPANX2; MGC119432
UniProt Protein Name
PANX2 protein
Protein Family
UniProt Gene Name
PANX2
UniProt Entry Name
Q495U3_HUMAN
NCBI Protein Information
pannexin-2; OTTHUMP00000028557; OTTHUMP00000196720

NCBI Summary for PANX2

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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UniProt Comments for PANX2

PANX2: Structural component of the gap junctions and the hemichannels. Belongs to the pannexin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: cytoplasm; plasma membrane; gap junction; integral to membrane

Molecular Function: gap junction hemi-channel activity

Biological Process: synaptic transmission; ion transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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