• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

STAG3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620274

STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be… More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STAG3, Polyclonal Antibody
Full Product Name
STAG3 (Stromal antigen 3, SCC3 homolog 3, cohesin subunit SA-3, stromalin 3)
Product Gene Name
anti-STAG3 antibody
Product Synonym Names
Anti -STAG3 (Stromal antigen 3, SCC3 homolog 3, cohesin subunit SA-3, stromalin 3)
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes STAG3. Sequence homology: human, mouse, rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
139,034 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (99775538..99812010). Location: 7q22.1
OMIM
608489
3D Structure
ModBase 3D Structure for Q9UJ98
Immunogen
Synthetic peptide corresponding to C-KHYNKFYEDYGD, from the internal region of STAG3 (NP_058660.2).

Product Categories/Family for anti-STAG3 antibody

Antibodies; Abs to Transcription Factors
Application Notes for anti-STAG3 antibody
Suitable for use in ELISA.
Dilution: ELISA: 1:32,000

Other Notes

Small volumes of anti-STAG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAG3 purchase

MBS620274 is an antibody targeting STAG3. Also known as STAG3 (Stromal antigen 3, SCC3 homolog 3, cohesin subunit SA-3, stromalin 3). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for STAG3. It may not necessarily be applicable to this product.

NCBI GI #
6114601
NCBI GeneID
10734
UniProt Primary Accession #
Q9UJ98
UniProt Secondary Accession #
Q8NDP3; A6H8Z1; D6W5U8
UniProt Related Accession #
Q9UJ98
NCBI Official Full Name
stromal antigen 3, (STAG3)
NCBI Official Synonym Full Names
stromal antigen 3
NCBI Official Symbol
STAG3
NCBI Official Synonym Symbols
STAG3
UniProt Protein Name
Cohesin subunit SA-3
UniProt Synonym Protein Names
SCC3 homolog 3; Stromal antigen 3; Stromalin-3
Protein Family
Cofilin
UniProt Gene Name
STAG3
UniProt Entry Name
STAG3_HUMAN
NCBI Protein Information
cohesin subunit SA-3; stromalin 3; stromalin-3; SCC3 homolog 3; OTTHUMP00000207376; OTTHUMP00000207395; OTTHUMP00000207396

NCBI Summary for STAG3

The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014]
Show more

UniProt Comments for STAG3

STAG3: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I. Belongs to the SCC3 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: extracellular space; nucleolus; synaptonemal complex; nucleus; chromosome, pericentric region

Biological Process: synaptonemal complex assembly

Disease: Premature Ovarian Failure 8
Show more

Research Articles on STAG3

1. we show evidence for the involvement of a common allele of STAG3 in the development of epithelial ovarian cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STAG3 antibody

 Products by Pathway  Pathway Diagram
 Oocyte Meiosis Pathway antibodies  Oocyte Meiosis Pathway Diagram
 Oocyte Meiosis Pathway antibodies  Oocyte Meiosis Pathway Diagram

Diseases associated with anti-STAG3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with STAG3 and Neoplasms
 Infertility, Male Antibodies  >3 publications with STAG3 and Infertility, Male
 Congenital Abnormalities Antibodies  >1 publications with STAG3 and Congenital Abnormalities
 Gonadal Disorders Antibodies  >1 publications with STAG3 and Gonadal Disorders

Organs/Tissues associated with anti-STAG3 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >9 publications with STAG3 and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000