SLITRK6 Antibody – Rabbit Polyclonal

SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains (1). Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2). Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas (3). Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

Small volumes of anti-SLITRK6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS620322 is an antibody targeting SLITRK6. Also known as Slitrk6, CT (SLIT and NTRK-like family 6, FLJ22774, FLJ22774, MGC119595, MGC119596, MGC119597, SLIT and NTRK-like protein 6 precursor). Reactive in Human, Mouse, Rat. Host: Rabbit.