• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Dermcidin, Aa66-80 (DCD) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620457

Dermcidin is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also… More details

$495 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dermcidin, aa66-80 (DCD), Polyclonal Antibody
Full Product Name
Dermcidin, aa66-80 (Preproteolysin, AIDD, DCD-1, DSEP, HCAP, MGC71930, PIF)
Product Gene Name
Product Synonym Names
Anti -Dermcidin, aa66-80 (Preproteolysin, AIDD, DCD-1, DSEP, HCAP, MGC71930, PIF)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 20ul sterile ddH2O.
Purity/Purification
Serum
Serum
Specificity
Recognizes human Dermcidin (aa66-80).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
11,284 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (55038375..55042149, complement). Location: 12q13.1
OMIM
606634
3D Structure
ModBase 3D Structure for P81605
Immunogen
Synthetic peptide corresponding to aa66-80, LEKGLDGAKKAVGGL, from human Dermcidin Peptide (polyLysine conjugated).

Product Categories/Family for anti-DCD antibody

Applications Tested/Suitable for anti-DCD antibody
ELISA (EL/EIA), Radioimmunoassay (RIA)
Application Notes for anti-DCD antibody
Suitable for use in ELISA and RIA.
Dilution: ELISA: 1:30,000
RIA: 1:5000

Other Notes

Small volumes of anti-DCD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCD purchase

MBS620457 is an antibody targeting DCD. Also known as Dermcidin, aa66-80 (Preproteolysin, AIDD, DCD-1, DSEP, HCAP, MGC71930, PIF). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DCD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dermcidin preproprotein
NCBI Official Synonym Full Names
dermcidin
NCBI Official Symbol
DCD
NCBI Official Synonym Symbols
PIF; AIDD; DSEP; HCAP; DCD-1; MGC71930
UniProt Protein Name
Dermcidin
UniProt Synonym Protein Names
Preproteolysin
UniProt Gene Name
DCD
UniProt Synonym Gene Names
AIDD; DSEP
UniProt Entry Name
DCD_HUMAN
NCBI Protein Information
dermcidin; preproteolysin; survival promoting peptide; proteolysis inducing factor; diffusible survival/evasion peptide

NCBI Summary for DCD

This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. [provided by RefSeq]
Show more

UniProt Comments for DCD

DCD: DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.-.-; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: extracellular region

Molecular Function: peptidase activity

Biological Process: killing of cells of another organism; defense response to bacterium; proteolysis; defense response to fungus
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000