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RAB17 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620534

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three… More details

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Product Overview

Online Datasheet in PDF
Product Name
Rab17, Polyclonal Antibody
Full Product Name
Rab17 (member RAS oncogene family, RAS-associated Protein RAB17)
Product Gene Name
anti-RAB17 antibody
Product Synonym Names
Anti -Rab17 (member RAS oncogene family, RAS-associated Protein RAB17)
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes mouse RAB17. Sequence homology: rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
23,475 Da
Chromosome Location
chromosome: 2; Location: 2q37.3
3D Structure
ModBase 3D Structure for Q6FIH2
Immunogen
Synthetic peptide corresponding to C-RKDSFHKAQQWLED from the internal region of mouse RAB17 (NP_033024.1).

Product Categories/Family for anti-RAB17 antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins
Applications Tested/Suitable for anti-RAB17 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-RAB17 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:64,000

Chemiluminescence of anti-RAB17 antibody

EB08314 (0.2µg/ml) staining of Mouse Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-RAB17 Polyclonal Antibody – Cat# MBS620534

Other Notes

Small volumes of anti-RAB17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB17 purchase

MBS620534 is an antibody targeting RAB17. Also known as Rab17 (member RAS oncogene family, RAS-associated Protein RAB17). Reactive in Mouse. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB17. It may not necessarily be applicable to this product.

NCBI GI #
49065334
NCBI GeneID
64284
UniProt Primary Accession #
Q6FIH2
UniProt Related Accession #
Q6FIH2; Q6PJZ0; Q9H0T7
NCBI Official Full Name
RAB17
NCBI Official Synonym Full Names
RAB17, member RAS oncogene family
NCBI Official Symbol
RAB17
NCBI Official Synonym Symbols
FLJ12538; RAB17
UniProt Protein Name
RAB17 protein
Protein Family
Ras-related protein
UniProt Gene Name
RAB17
UniProt Entry Name
Q6FIH2_HUMAN
NCBI Protein Information
ras-related protein Rab-17; OTTHUMP00000202805

NCBI Summary for RAB17

The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM]

UniProt Comments for RAB17

RAB17: Might be involved in transcellular transport. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric, Rab; G protein, monomeric

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: recycling endosome; cell soma; recycling endosome membrane; endocytic vesicle; basolateral plasma membrane; apical plasma membrane; dendrite; early endosome; plasma membrane; melanosome; intracellular

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: filopodium formation; metabolic process; regulation of dendrite development; regulation of filopodium formation; transcytosis; endocytic recycling; melanosome transport; intracellular protein transport; regulation of synaptogenesis; regulation of endocytosis; establishment of melanosome localization; cilium biogenesis; Rab protein signal transduction; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
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Research Articles on RAB17

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB17 antibody

 Reference Product  PubMed Publications
 RABAC1 antibody  >1 publications with RAB17 and RABAC1

Diseases associated with anti-RAB17 antibody

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >1 publications with RAB17 and Carcinoma, Hepatocellular
 Ataxia Antibodies  >1 publications with RAB17 and Ataxia
 Carcinoma Antibodies  >1 publications with RAB17 and Carcinoma
 Neoplasms Antibodies  >1 publications with RAB17 and Neoplasms
 Adenocarcinoma Antibodies  >1 publications with RAB17 and Adenocarcinoma
 Liver Diseases Antibodies  >1 publications with RAB17 and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with RAB17 and Liver Neoplasms

Organs/Tissues associated with anti-RAB17 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4 publications with RAB17 and Kidney
 Embryonic Tissue Antibodies  >3 publications with RAB17 and Embryonic Tissue
 Liver Antibodies  >3 publications with RAB17 and Liver
 Brain Antibodies  >2 publications with RAB17 and Brain
 Intestine Antibodies  >2 publications with RAB17 and Intestine
 Placenta Antibodies  >1 publications with RAB17 and Placenta
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