Goat Anti-HOXB4 Polyclonal Antibody – Cat# MBS620540

Hox B4 (HOXB4) Antibody – Goat Polyclonal

Name: HOXB4 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS620540
Price: 610 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620540

Homebox transcription factors (Hox) are encoded by highly conserved developmental genes that are involved embryonic and early hematopoietic development. Specifically, Homeobox B4 (HoxB4) is a transcription factor encoded by HOXB4 gene and it is involved in… More details

$610 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Hox B4 (HOXB4), Polyclonal Antibody

Full Product Name

Hox B4 (Homeobox Protein B4, HOXB4, HOX-B4, Homeobox 2F, Hox 2F, HOX 2, Hox 2.6)

Product Gene Name

anti-HOXB4 antibody

Product Synonym Names

Anti -Hox B4 (Homeobox Protein B4, HOXB4, HOX-B4, Homeobox 2F, Hox 2F, HOX 2, Hox 2.6)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by affinity chromatography.

Specificity

Recognizes human Hox B4. Species sequence homology: mouse.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

27,604 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (46652869..46655743, complement). Location: 17q21.32

OMIM

142965

3D Structure

ModBase 3D Structure for P17483

Immunogen

Synthetic peptide with sequence C-EYSQSDYLPSDH, from the internal region of human Hox B4 (NP_076920.1).

Product Categories/Family for anti-HOXB4 antibody

Antibodies; Abs to Homeobox (HOX)

Applications Tested/Suitable for anti-HOXB4 antibody

ELISA (EL/EIA)

Application Notes for anti-HOXB4 antibody

Suitable for use in ELISA.
Dilution: ELISA: 1:32000

Other Notes

Small volumes of anti-HOXB4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOXB4 purchase

MBS620540 is an antibody targeting HOXB4. Also known as Hox B4 (Homeobox Protein B4, HOXB4, HOX-B4, Homeobox 2F, Hox 2F, HOX 2, Hox 2.6). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXB4. It may not necessarily be applicable to this product.

NCBI GI #

13273315

NCBI GeneID

3214

NCBI Accession #

NP_076920.1

UniProt Primary Accession #

P17483

UniProt Secondary Accession #

Q9NTA0

UniProt Related Accession #

P17483

GenBank Nucleotide #

NM_024015.4

NCBI Official Full Name

homeobox protein Hox-B4

NCBI Official Synonym Full Names

homeobox B4

NCBI Official Symbol

HOXB4

NCBI Official Synonym Symbols

HOX2; HOX2F; HOX-2.6

UniProt Protein Name

Homeobox protein Hox-B4

UniProt Synonym Protein Names

Homeobox protein Hox-2.6; Homeobox protein Hox-2F

Protein Family

Homeobox protein

UniProt Gene Name

HOXB4

UniProt Synonym Gene Names

HOX2F

UniProt Entry Name

HXB4_HUMAN

NCBI Protein Information

homeobox protein Hox-B4; homeo box 2F; homeo box B4; OTTHUMP00000217026; homeobox protein Hox-2F; homeobox protein Hox-2.6

NCBI Summary for HOXB4

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq]

UniProt Comments for HOXB4

HOXB4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Deformed subfamily.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: bone marrow development; anterior/posterior pattern formation; spleen development; cell proliferation; transcription, DNA-dependent; morphogenesis of an epithelial sheet; somatic stem cell division; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; embryonic skeletal morphogenesis

Research Articles on HOXB4

1. Downregulation of HoxB2, HoxB4 and Alx4 expression during the narrow window of early embryogenesis may cause omphalocele in the Cd chick model by interfering with molecular signaling required for proper VBW formation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HOXB4 antibody

Reference Product	PubMed Publications
MEIS1 antibody	>8 publications with HOXB4 and MEIS1

Diseases associated with anti-HOXB4 antibody

Disease Name	Pubmed Publications
Leukemia Antibodies	>42 publications with HOXB4 and Leukemia
Neoplasms Antibodies	>31 publications with HOXB4 and Neoplasms
Leukemia, Myeloid Antibodies	>25 publications with HOXB4 and Leukemia, Myeloid
Leukemia, Myeloid, Acute Antibodies	>8 publications with HOXB4 and Leukemia, Myeloid, Acute
Lung Diseases Antibodies	>3 publications with HOXB4 and Lung Diseases
Breast Neoplasms Antibodies	>2 publications with HOXB4 and Breast Neoplasms
Lung Neoplasms Antibodies	>2 publications with HOXB4 and Lung Neoplasms
Neural Tube Defects Antibodies	>2 publications with HOXB4 and Neural Tube Defects
Lymphoma Antibodies	>2 publications with HOXB4 and Lymphoma
Central Nervous System Diseases Antibodies	>1 publications with HOXB4 and Central Nervous System Diseases

Organs/Tissues associated with anti-HOXB4 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>9 publications with HOXB4 and Skin
Heart Antibodies	>7 publications with HOXB4 and Heart
Lung Antibodies	>6 publications with HOXB4 and Lung
Muscle Antibodies	>2 publications with HOXB4 and Muscle
Pancreas Antibodies	>2 publications with HOXB4 and Pancreas
Mammary Gland Antibodies	>1 publications with HOXB4 and Mammary Gland
Connective Tissue Antibodies	>1 publications with HOXB4 and Connective Tissue
Kidney Antibodies	>1 publications with HOXB4 and Kidney
Uterus Antibodies	>1 publications with HOXB4 and Uterus