Goat Anti-GLIPR1 Polyclonal Antibody – Cat# MBS620665

GLIPR1 Antibody – Goat Polyclonal

Name: GLIPR1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS620665
Price: 610 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620665

MBS620665 is an antibody targeting GLIPR1. Also known as GLIPR1 (RTVP-1, GLI pathogenesis-related 1 (glioma), CRISP7, GLIPR, RTVP1, Glioma pathogenesis-related protein). Reactive in Human. Host: Goat. More details

$610 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GLIPR1, Polyclonal Antibody

Full Product Name

GLIPR1 (RTVP-1, GLI pathogenesis-related 1 (glioma), CRISP7, GLIPR, RTVP1, Glioma pathogenesis-related protein)

Product Gene Name

anti-GLIPR1 antibody

Product Synonym Names

Anti -GLIPR1 (RTVP-1, GLI pathogenesis-related 1 (glioma), CRISP7, GLIPR, RTVP1, Glioma pathogenesis-related protein)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by affinity chromatography.

Specificity

Recognizes human GLIPR1.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

30,366 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (75874513..75895716). Location: 12q21.2

OMIM

602692

3D Structure

ModBase 3D Structure for P48060

Immunogen

A synthetic peptide from the C-terminus of aa--NRQRDQVKRYYS

Product Categories/Family for anti-GLIPR1 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-GLIPR1 antibody

ELISA (EL/EIA)

Application Notes for anti-GLIPR1 antibody

Suitable for use in ELISA.
Dilution: Peptide ELISA: 1:64,000.
Western Blot: Preliminary experiments gave an approx 40kD band in human prostate lysates after 1ug/ml antibody staining.

Other Notes

Small volumes of anti-GLIPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GLIPR1. It may not necessarily be applicable to this product.

NCBI GI #

110825980

NCBI GeneID

11010

NCBI Accession #

NP_006842.2

UniProt Primary Accession #

P48060

UniProt Secondary Accession #

Q15409; Q969K2

UniProt Related Accession #

P48060

GenBank Nucleotide #

NM_006851.2

NCBI Official Full Name

glioma pathogenesis-related protein 1

NCBI Official Synonym Full Names

GLI pathogenesis-related 1

NCBI Official Symbol

GLIPR1

NCBI Official Synonym Symbols

GLIPR; RTVP1; CRISP7

UniProt Protein Name

Glioma pathogenesis-related protein 1

UniProt Synonym Protein Names

Protein RTVP-1

Protein Family

Glioma pathogenesis-related protein

UniProt Gene Name

GLIPR1

UniProt Synonym Gene Names

GLIPR; RTVP1

UniProt Entry Name

GLIP1_HUMAN

NCBI Protein Information

glioma pathogenesis-related protein 1; gliPR 1; protein RTVP-1; GLI pathogenesis-related 1 (glioma); testes-specific vespid and pathogenesis protein 1; related to testis-specific, vespid, and pathogenesis proteins 1

NCBI Summary for GLIPR1

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]

UniProt Comments for GLIPR1

GLIPR1: a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q21.2

Cellular Component: membrane; plasma membrane; extracellular region; integral to membrane

Biological Process: cellular lipid metabolic process

Research Articles on GLIPR1

1. GLIPR1 expression is downregulated or even lost by promoter methylation in acute myeloid leukemia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GLIPR1 antibody

Products by Pathway	Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies	Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram

Diseases associated with anti-GLIPR1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>17 publications with GLIPR1 and Neoplasms
Glioma Antibodies	>14 publications with GLIPR1 and Glioma
Prostatic Diseases Antibodies	>7 publications with GLIPR1 and Prostatic Diseases
Genital Diseases, Male Antibodies	>7 publications with GLIPR1 and Genital Diseases, Male
Prostatic Neoplasms Antibodies	>7 publications with GLIPR1 and Prostatic Neoplasms
Breast Neoplasms Antibodies	>3 publications with GLIPR1 and Breast Neoplasms
Nervous System Diseases Antibodies	>3 publications with GLIPR1 and Nervous System Diseases
Cell Transformation, Neoplastic Antibodies	>2 publications with GLIPR1 and Cell Transformation, Neoplastic
Neoplasm Metastasis Antibodies	>2 publications with GLIPR1 and Neoplasm Metastasis
Neoplasm Invasiveness Antibodies	>2 publications with GLIPR1 and Neoplasm Invasiveness

Organs/Tissues associated with anti-GLIPR1 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>14 publications with GLIPR1 and Prostate
Brain Antibodies	>6 publications with GLIPR1 and Brain
Bone Antibodies	>4 publications with GLIPR1 and Bone
Lung Antibodies	>4 publications with GLIPR1 and Lung
Testis Antibodies	>4 publications with GLIPR1 and Testis
Bone Marrow Antibodies	>3 publications with GLIPR1 and Bone Marrow
Blood Antibodies	>2 publications with GLIPR1 and Blood
Kidney Antibodies	>2 publications with GLIPR1 and Kidney
Bladder Antibodies	>1 publications with GLIPR1 and Bladder
Mammary Gland Antibodies	>1 publications with GLIPR1 and Mammary Gland