Mouse Anti-KIF3B Monoclonal Antibody – Cat# MBS6207047

KIF3B Antibody – Mouse Monoclonal

Name: KIF3B Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS6207047
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6207047

The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KIF3B, Monoclonal Antibody

Full Product Name

KIF3B (Kinesin Family Member 3B, HH0048, KIAA0359) (MaxLight 490)

Product Gene Name

anti-KIF3B antibody

Product Synonym Names

Kinesin Family Member 3B; HH0048; KIAA0359

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

8H4

Host

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified

Specificity

Recognizes KIF3B.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

85,125 Da

Chromosome Location

Chromosome: 20; NC_000020.10 (30865443..30922814). Location: 20q11.21

OMIM

603754

3D Structure

ModBase 3D Structure for O15066

Immunogen

KIF3B (NP_004789.1, 648aa-747aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQSRGLVPK

Conjugate

MaxLight490

Product Categories/Family for anti-KIF3B antibody

Antibodies; Motor Proteins

Applications Tested/Suitable for anti-KIF3B antibody

Western Blot (WB)

Application Notes for anti-KIF3B antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-KIF3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIF3B purchase

MBS6207047 is an antibody targeting KIF3B. Also known as KIF3B (Kinesin Family Member 3B, HH0048, KIAA0359) (MaxLight 490). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF3B. It may not necessarily be applicable to this product.

NCBI GI #

4758646

NCBI GeneID

9371

NCBI Accession #

NP_004789.1

UniProt Primary Accession #

O15066

UniProt Secondary Accession #

B2RMP4; E1P5M5

UniProt Related Accession #

O15066

GenBank Nucleotide #

NM_004798.3

NCBI Official Full Name

kinesin-like protein KIF3B

NCBI Official Synonym Full Names

kinesin family member 3B

NCBI Official Symbol

KIF3B

NCBI Official Synonym Symbols

FLA8; HH0048; KLP-11

UniProt Protein Name

Kinesin-like protein KIF3B

UniProt Synonym Protein Names

HH0048; Microtubule plus end-directed kinesin motor 3B

Protein Family

Kinesin-like protein

UniProt Gene Name

KIF3B

UniProt Synonym Gene Names

KIAA0359

UniProt Entry Name

KIF3B_HUMAN

NCBI Protein Information

kinesin-like protein KIF3B; microtubule plus end-directed kinesin motor 3B

UniProt Comments for KIF3B

KIF3B: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Belongs to the kinesin-like protein family. Kinesin II subfamily.

Protein type: Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 20q11.21

Cellular Component: plus-end kinesin complex; microtubule cytoskeleton; centrosome; membrane; spindle microtubule; kinesin II complex; midbody; cytosol

Molecular Function: protein binding; Rho GTPase binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding

Biological Process: positive regulation of cytokinesis; mitotic centrosome separation; mitotic spindle organization and biogenesis; metabolic process; organelle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytoskeleton-dependent intracellular transport; determination of left/right symmetry; anterograde axon cargo transport; blood coagulation; microtubule-based movement

Research Articles on KIF3B

1. KIF3B is involved in the trafficking of kAE1 to the plasma membrane of human kidney alpha-intercalated cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KIF3B antibody

Reference Product	PubMed Publications
KIF3A antibody	>30 publications with KIF3B and KIF3A
KIF3C antibody	>12 publications with KIF3B and KIF3C
KIFAP3 antibody	>3 publications with KIF3B and KIFAP3
ARHGEF10 antibody	>1 publications with KIF3B and ARHGEF10
PKP4 antibody	>1 publications with KIF3B and PKP4
IFT20 antibody	>1 publications with KIF3B and IFT20

Pathways associated with anti-KIF3B antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Kinesins Pathway antibodies	Kinesins Pathway Diagram
MHC Class II Antigen Presentation Pathway antibodies	MHC Class II Antigen Presentation Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies	Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram

Diseases associated with anti-KIF3B antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>2 publications with KIF3B and Kidney Diseases
Nervous System Diseases Antibodies	>2 publications with KIF3B and Nervous System Diseases
Congenital Abnormalities Antibodies	>2 publications with KIF3B and Congenital Abnormalities
Heart Defects, Congenital Antibodies	>1 publications with KIF3B and Heart Defects, Congenital
Adenocarcinoma Antibodies	>1 publications with KIF3B and Adenocarcinoma
Brain Diseases Antibodies	>1 publications with KIF3B and Brain Diseases
Fetal Growth Retardation Antibodies	>1 publications with KIF3B and Fetal Growth Retardation
Respiratory System Abnormalities Antibodies	>1 publications with KIF3B and Respiratory System Abnormalities

Organs/Tissues associated with anti-KIF3B antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>10 publications with KIF3B and Brain
Kidney Antibodies	>8 publications with KIF3B and Kidney
Nerve Antibodies	>6 publications with KIF3B and Nerve
Testis Antibodies	>5 publications with KIF3B and Testis
Heart Antibodies	>4 publications with KIF3B and Heart
Eye Antibodies	>4 publications with KIF3B and Eye
Embryonic Tissue Antibodies	>3 publications with KIF3B and Embryonic Tissue
Muscle Antibodies	>3 publications with KIF3B and Muscle
Blood Antibodies	>2 publications with KIF3B and Blood
Ganglia Antibodies	>2 publications with KIF3B and Ganglia