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FEZ2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS620708

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76 (1,2). In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-… More details

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Product Overview

Online Datasheet in PDF
Product Name
FEZ2, IN, Polyclonal Antibody
Full Product Name
FEZ2, IN (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK cell-associated protein 3Cl, Zygin-2, Zygin II)
Product Gene Name
Product Synonym Names
Anti -FEZ2, IN (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK cell-associated protein 3Cl, Zygin-2, Zygin II)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human FEZ2. Species crossreactivity: Mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
39,557 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (36779401..36825332, complement). Location: 2p21
3D Structure
ModBase 3D Structure for Q0D2I6
Immunogen
Synthetic peptide corresponding to 15aa from near the center of human FEZ2 (Genbank accession No. NP_001036013).
Applications Tested/Suitable for anti-FEZ2 antibody
Western Blot (WB)
Application Notes for anti-FEZ2 antibody
Dilution: Western Blot: 0.5-1ug/ml

Western Blot (WB) of anti-FEZ2 antibody

Western blot analysis of Plxdc2 in human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.
Rabbit Anti-FEZ2 Polyclonal Antibody – Cat# MBS620708

Other Notes

Small volumes of anti-FEZ2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FEZ2 purchase

MBS620708 is an antibody targeting FEZ2. Also known as FEZ2, IN (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK cell-associated protein 3Cl, Zygin-2, Zygin II). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FEZ2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fasciculation and elongation protein zeta-2 isoform 2
NCBI Official Synonym Full Names
fasciculation and elongation protein zeta 2 (zygin II)
NCBI Official Symbol
FEZ2
NCBI Official Synonym Symbols
HUM3CL; MGC117372
UniProt Protein Name
Fasciculation and elongation protein zeta 2 (Zygin II)
UniProt Gene Name
FEZ2
UniProt Entry Name
Q0D2I6_HUMAN
NCBI Protein Information
fasciculation and elongation protein zeta-2; zygin 2; zygin-2; zygin II; OTTHUMP00000201286; OTTHUMP00000201287; OTTHUMP00000201289; OTTHUMP00000201293; pre-T/NK cell associated protein (3Cl)

NCBI Summary for FEZ2

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq]

UniProt Comments for FEZ2

FEZ2: Involved in axonal outgrowth and fasciculation. Belongs to the zygin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 2p21

Molecular Function: protein binding

Biological Process: axon guidance; nervous system development; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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