Mouse Anti-LFNG Monoclonal Antibody – Cat# MBS6207147

LFNG Antibody – Mouse Monoclonal

Name: LFNG Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS6207147
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6207147

This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LFNG, Monoclonal Antibody

Full Product Name

LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, SCDO3) (MaxLight 490)

Product Gene Name

anti-LFNG antibody

Product Synonym Names

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

3D12

Host

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified

Specificity

Recognizes LFNG.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunogen

LFNG (AAH14851, 1aa-250aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MTPGRCCLAADIQVETFIFTDGEDEALARHTGNVVITNCSAAHSRQALSCKMAVEYDRFIESGRKWFCHVDDDNYVNLRALLRLLASYPHTRDVYVGKPSLDRPIQAMERVSENKVRPVHFWFATGGAGFCISRGLALKMSPWASGGHFMNTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTSELHEQVTLSYGMFENKRNAVHVKGPFSVEADPSRFRSIHCHLYPDTPWCPRTAIF

Conjugate

MaxLight490

Product Categories/Family for anti-LFNG antibody

Antibodies; Enzymes; Glycosyltransferase

Applications Tested/Suitable for anti-LFNG antibody

Western Blot (WB)

Application Notes for anti-LFNG antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-LFNG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LFNG purchase

MBS6207147 is an antibody targeting LFNG. Also known as LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, SCDO3) (MaxLight 490). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LFNG. It may not necessarily be applicable to this product.

NCBI GI #

15990390

NCBI GeneID

3955

NCBI Accession #

AAH14851

UniProt Related Accession #

Q8NES3

NCBI Official Full Name

LFNG protein

NCBI Official Synonym Full Names

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

NCBI Official Symbol

LFNG

NCBI Official Synonym Symbols

SCDO3

Protein Family

Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

NCBI Protein Information

beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

NCBI Summary for LFNG

This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. [provided by RefSeq, May 2018]

Research Articles on LFNG

1. LFNG mutation is associated with spondylocostal dysostosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LFNG antibody

Reference Product	PubMed Publications
NOTCH1 antibody	>38 publications with LFNG and NOTCH1
HES7 antibody	>30 publications with LFNG and HES7
MESP2 antibody	>24 publications with LFNG and MESP2
NOTCH2 antibody	>12 publications with LFNG and NOTCH2
NOTCH3 antibody	>2 publications with LFNG and NOTCH3
B4GALT1 antibody	>1 publications with LFNG and B4GALT1

Pathways associated with anti-LFNG antibody

Products by Pathway	Pathway Diagram
Delta-Notch Signaling Pathway antibodies	Delta-Notch Signaling Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram
Notch Signaling Pathway antibodies	Notch Signaling Pathway Diagram
Other Types Of O-glycan Biosynthesis Pathway antibodies	Other Types Of O-glycan Biosynthesis Pathway Diagram
Other Types Of O-glycan Biosynthesis Pathway antibodies	Other Types Of O-glycan Biosynthesis Pathway Diagram
Pre-NOTCH Expression And Processing Pathway antibodies	Pre-NOTCH Expression And Processing Pathway Diagram
Pre-NOTCH Processing In Golgi Pathway antibodies	Pre-NOTCH Processing In Golgi Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By NOTCH Pathway antibodies	Signaling By NOTCH Pathway Diagram

Diseases associated with anti-LFNG antibody

Disease Name	Pubmed Publications
Abnormalities, Multiple Antibodies	>14 publications with LFNG and Abnormalities, Multiple
Congenital Abnormalities Antibodies	>12 publications with LFNG and Congenital Abnormalities
Disease Models, Animal Antibodies	>8 publications with LFNG and Disease Models, Animal
Nervous System Diseases Antibodies	>5 publications with LFNG and Nervous System Diseases
Cardiovascular Diseases Antibodies	>4 publications with LFNG and Cardiovascular Diseases
Nervous System Malformations Antibodies	>2 publications with LFNG and Nervous System Malformations
Infertility, Female Antibodies	>2 publications with LFNG and Infertility, Female
SPONDYLOCOSTAL DYSOSTOSIS 3, AUTOSOMAL RECESSIVE Antibodies	>2 publications with LFNG and SPONDYLOCOSTAL DYSOSTOSIS 3, AUTOSOMAL RECESSIVE
Abnormalities, Drug-Induced Antibodies	>1 publications with LFNG and Abnormalities, Drug-Induced
Adenocarcinoma Antibodies	>1 publications with LFNG and Adenocarcinoma

Organs/Tissues associated with anti-LFNG antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>30 publications with LFNG and Embryonic Tissue
Blood Antibodies	>19 publications with LFNG and Blood
Brain Antibodies	>14 publications with LFNG and Brain
Thymus Antibodies	>9 publications with LFNG and Thymus
Kidney Antibodies	>6 publications with LFNG and Kidney
Heart Antibodies	>5 publications with LFNG and Heart
Lung Antibodies	>3 publications with LFNG and Lung
Eye Antibodies	>3 publications with LFNG and Eye
Connective Tissue Antibodies	>2 publications with LFNG and Connective Tissue
Prostate Antibodies	>1 publications with LFNG and Prostate