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NEUROG1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6207556

MBS6207556 is an antibody targeting NEUROG1. Also known as NEUROG1 (Neurogenin 1, AKA, Math4C, NEUROD3, bHLHa6, ngn1) (MaxLight 490). Host: Mouse. Mouse monoclonal antibody raised against a partial recombinant NEUROG1. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NEUROG1, Monoclonal Antibody
Full Product Name
NEUROG1 (Neurogenin 1, AKA, Math4C, NEUROD3, bHLHa6, ngn1) (MaxLight 490)
Product Gene Name
anti-NEUROG1 antibody
Product Synonym Names
Neurogenin 1; AKA; Math4C; NEUROD3; bHLHa6; ngn1
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4G10
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified
Specificity
Recognizes NEUROG1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
25,718 Da
OMIM
601726
3D Structure
ModBase 3D Structure for Q92886
Immunogen
NEUROG1 (NP_006152, 82aa-163aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
SEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGARER
Conjugate
MaxLight490

Product Categories/Family for anti-NEUROG1 antibody

Antibodies; Transcription Factors
Applications Tested/Suitable for anti-NEUROG1 antibody
Western Blot (WB)
Application Notes for anti-NEUROG1 antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-NEUROG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NEUROG1. It may not necessarily be applicable to this product.

NCBI GI #
38455396
NCBI GeneID
4762
NCBI Accession #
NP_006152
UniProt Primary Accession #
Q92886
UniProt Secondary Accession #
Q5U0Q9; Q96HE1
UniProt Related Accession #
Q92886
GenBank Nucleotide #
NM_006161.2
NCBI Official Full Name
neurogenin-1
NCBI Official Synonym Full Names
neurogenin 1
NCBI Official Symbol
NEUROG1
NCBI Official Synonym Symbols
AKA; ngn1; Math4C; bHLHa6; NEUROD3
UniProt Protein Name
Neurogenin-1
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3
Protein Family
Neurogenin
UniProt Gene Name
NEUROG1
UniProt Synonym Gene Names
BHLHA6; NEUROD3; NGN; NGN1; NGN-1; bHLHa6; NeuroD3
UniProt Entry Name
NGN1_HUMAN
NCBI Protein Information
neurogenin-1

UniProt Comments for NEUROG1

neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis.

Protein type: Transcription factor; Cell development/differentiation; DNA-binding

Chromosomal Location of Human Ortholog: 5q23-q31

Cellular Component: perikaryon; nucleus

Molecular Function: protein dimerization activity; DNA binding; chromatin binding; transcription factor activity

Biological Process: neuron differentiation; regulation of transcription from RNA polymerase II promoter; nervous system development; inner ear morphogenesis; cell fate commitment; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; positive regulation of exit from mitosis
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Research Articles on NEUROG1

1. NeuroD1 seemed not sufficient to induce and maintain neuronal differentiation. Induction of neuronal differentiation by overexpression of Neurog1 initiated important steps for the development of glutamatergic neurons such as the spiral ganglion neurons

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NEUROG1 antibody

 Reference Product  PubMed Publications
 CACNA1G antibody  >49 publications with NEUROG1 and CACNA1G
 RUNX3 antibody  >47 publications with NEUROG1 and RUNX3
 CTNNB1 antibody  >15 publications with NEUROG1 and CTNNB1
 SHH antibody  >10 publications with NEUROG1 and SHH
 KCTD11 antibody  >1 publications with NEUROG1 and KCTD11
 POU4F1 antibody  >1 publications with NEUROG1 and POU4F1
 ASB11 antibody  >1 publications with NEUROG1 and ASB11

Pathways associated with anti-NEUROG1 antibody

 Products by Pathway  Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram

Diseases associated with anti-NEUROG1 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >8 publications with NEUROG1 and Brain Diseases
 Drug Toxicity Antibodies  >5 publications with NEUROG1 and Drug Toxicity
 Congenital Abnormalities Antibodies  >4 publications with NEUROG1 and Congenital Abnormalities
 Neural Tube Defects Antibodies  >3 publications with NEUROG1 and Neural Tube Defects
 Inflammation Antibodies  >2 publications with NEUROG1 and Inflammation
 Necrosis Antibodies  >2 publications with NEUROG1 and Necrosis
 Hyperplasia Antibodies  >2 publications with NEUROG1 and Hyperplasia
 Eye Abnormalities Antibodies  >1 publications with NEUROG1 and Eye Abnormalities
 Liver Diseases Antibodies  >1 publications with NEUROG1 and Liver Diseases
 Hypertrophy Antibodies  >1 publications with NEUROG1 and Hypertrophy

Organs/Tissues associated with anti-NEUROG1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >77 publications with NEUROG1 and Brain
 Eye Antibodies  >19 publications with NEUROG1 and Eye
 Pineal Gland Antibodies  >1 publications with NEUROG1 and Pineal Gland
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