Mouse Anti-L3MBTL2 Monoclonal Antibody – Cat# MBS6212263

L3MBTL2 Antibody – Mouse Monoclonal

Name: L3MBTL2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6212263
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6212263

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

L3MBTL2, Monoclonal Antibody

Full Product Name

L3MBTL2 (Lethal(3)malignant Brain Tumor-like Protein 2, H-l(3)mbt-like Protein 2, L(3)mbt-like Protein 2) (MaxLight 550)

Product Gene Name

anti-L3MBTL2 antibody

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

4F4

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human L3MBTL2.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

79kDa

OMIM

611865

3D Structure

ModBase 3D Structure for Q969R5

Immunogen

Partial recombinant corresponding to aa642-706 from human L3MBTL2 (NP_113676) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

RQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD

Conjugate

MaxLight550

Product Categories/Family for anti-L3MBTL2 antibody

Antibodies; Cancer Markers

Applications Tested/Suitable for anti-L3MBTL2 antibody

FLISA, Western Blot (WB)

Application Notes for anti-L3MBTL2 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-L3MBTL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for L3MBTL2 purchase

MBS6212263 is an antibody targeting L3MBTL2. Also known as L3MBTL2 (Lethal(3)malignant Brain Tumor-like Protein 2, H-l(3)mbt-like Protein 2, L(3)mbt-like Protein 2) (MaxLight 550). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for L3MBTL2. It may not necessarily be applicable to this product.

NCBI GI #

20149698

NCBI GeneID

83746

NCBI Accession #

NP_113676

UniProt Primary Accession #

Q969R5

UniProt Related Accession #

Q969R5

GenBank Nucleotide #

NM_031488

NCBI Official Full Name

lethal(3)malignant brain tumor-like protein 2

NCBI Official Synonym Full Names

L3MBTL histone methyl-lysine binding protein 2

NCBI Official Symbol

L3MBTL2

NCBI Official Synonym Symbols

L3MBT; H-l(3)mbt-l

UniProt Protein Name

Lethal(3)malignant brain tumor-like protein 2

Protein Family

Lethal(3)malignant brain tumor-like protein

UniProt Gene Name

L3MBTL2

UniProt Synonym Gene Names

H-l(3)mbt-like protein 2

UniProt Entry Name

LMBL2_HUMAN

NCBI Protein Information

lethal(3)malignant brain tumor-like protein 2

UniProt Comments for L3MBTL2

Function: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. Ref.12

Subunit structure: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.

Subcellular location: Nucleus

Probable.

Sequence similarities: Contains 1 FCS-type zinc finger.Contains 4 MBT repeats.

Sequence caution: The sequence BAB84917.1 differs from that shown. Reason: Intron retention.The sequence BAC04936.1 differs from that shown. Reason: Intron retention.

Research Articles on L3MBTL2

1. L3MBTL2 polymorphism is associated with neuroticism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-L3MBTL2 antibody

Reference Product	PubMed Publications
E2F6 antibody	>3 publications with L3MBTL2 and E2F6
HDAC3 antibody	>1 publications with L3MBTL2 and HDAC3
RB1 antibody	>1 publications with L3MBTL2 and RB1
PCGF6 antibody	>1 publications with L3MBTL2 and PCGF6
CBX3 antibody	>1 publications with L3MBTL2 and CBX3

Organs/Tissues associated with anti-L3MBTL2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with L3MBTL2 and Brain
Bone Antibodies	>1 publications with L3MBTL2 and Bone
Bone Marrow Antibodies	>1 publications with L3MBTL2 and Bone Marrow