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Urea Transporter A1 (SLC14A2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS621227

UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates transepithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney… More details

$755 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Urea Transporter A1 (SLC14A2), Polyclonal Antibody
Full Product Name
Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2)
Product Gene Name
Product Synonym Names
Anti -Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Purity/Purification
Affinity by Purified Chromatography
Concentration
1mg/ml (lot specific)
Specificity
Recognizes rat UT-A1 at ~97kD and 127 kD. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Chromosome Location
Chromosome: 18; NC_000018.9 (42792947..43263072). Location: 18q12.1-q21.1
OMIM
601611
3D Structure
ModBase 3D Structure for Q15849
Immunogen
Synthetic peptide corresponding to aa911-929 of the C-terminal tail of rat UT-A1 (NP_062220).
Applications Tested/Suitable for anti-SLC14A2 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-SLC14A2 antibody
Suitable for use in Western Blot and Immunocytochemistry.
Dilution:
Western Blot: 1:1000. 1ug/ml detected UT-A1 in 20 ug of rat kidney tissue lysate by colorimetric immunoblot analysis using IgG goat x rabbit (HRP) as the secondary antibody. Optimal diluitons to be determined by the researcher.

Other Notes

Small volumes of anti-SLC14A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC14A2 purchase

MBS621227 is an antibody targeting SLC14A2. Also known as Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC14A2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
urea transporter 2
NCBI Official Synonym Full Names
solute carrier family 14 (urea transporter), member 2
NCBI Official Symbol
SLC14A2
NCBI Official Synonym Symbols
UT2; UTA; UTR; HUT2; UT-A2; hUT-A6
UniProt Protein Name
Urea transporter 2
UniProt Synonym Protein Names
Solute carrier family 14 member 2; Urea transporter, kidney
Protein Family
UniProt Gene Name
SLC14A2
UniProt Synonym Gene Names
HUT2; UT2
UniProt Entry Name
UT2_HUMAN
NCBI Protein Information
urea transporter 2; urea transporter-2; urea transporter, kidney; solute carrier family 14 member 2

NCBI Summary for SLC14A2

The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
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UniProt Comments for SLC14A2

SLC14A2: Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism. Belongs to the urea transporter family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.1-q21.1

Cellular Component: membrane; apical plasma membrane; integral to membrane; plasma membrane

Molecular Function: protein binding; urea transmembrane transporter activity; cell adhesion molecule binding

Biological Process: urea transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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