Mouse Anti-MRPL12 Monoclonal Antibody – Cat# MBS6212591

MRPL12 Antibody – Mouse Monoclonal

Name: MRPL12 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6212591
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6212591

MBS6212591 is an antibody targeting MRPL12. Also known as MRPL12 (Mitochondrial Ribosomal Protein L12, 39S Ribosomal Protein L12, Mitochondrial, 5c5-2, FLJ60124, L12mt, MGC8610, MRP-L12, MRP-L31/34, MRPL7, MRPL7/L12, RPML12) (MaxLight 550). Reactive in Human.… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MRPL12, Monoclonal Antibody

Full Product Name

MRPL12 (Mitochondrial Ribosomal Protein L12, 39S Ribosomal Protein L12, Mitochondrial, 5c5-2, FLJ60124, L12mt, MGC8610, MRP-L12, MRP-L31/34, MRPL7, MRPL7/L12, RPML12) (MaxLight 550)

Product Gene Name

anti-MRPL12 antibody

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

3B12-1A3

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human MRPL12.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

21,348 Da

Immunogen

Full length recombinant corresponding to aa1-199 from human MRPL12 (AAH02344) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MLPAAARPLWGPCLGLRAAAFRLARRQVPCVCAVRHMRSSGHQRCEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLVPMGGVMSGAVPAAAAQEAVEEDIPIAKERTHFTVRLTEAKPVDKVKLIKEIKNYIQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE

Conjugate

MaxLight550

Product Categories/Family for anti-MRPL12 antibody

Antibodies; Mitochondrial Proteins

Applications Tested/Suitable for anti-MRPL12 antibody

FLISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-MRPL12 antibody

IF: 10ug/ml
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-MRPL12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRPL12. It may not necessarily be applicable to this product.

NCBI GI #

33876585

NCBI GeneID

6182

NCBI Accession #

BC002344

NCBI Related Accession #

AAH02344

UniProt Secondary Accession #

Q969U0; Q9HCA2; Q9UQJ3

UniProt Related Accession #

P52815

NCBI Official Full Name

Homo sapiens mitochondrial ribosomal protein L12, mRNA

NCBI Official Synonym Full Names

mitochondrial ribosomal protein L12

NCBI Official Symbol

MRPL12

NCBI Official Synonym Symbols

5c5-2; L12mt; MRPL7; RPML12; MRPL7/L12; MRP-L31/34

Protein Family

39S ribosomal protein

NCBI Protein Information

39S ribosomal protein L12, mitochondrial

NCBI Summary for MRPL12

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008]

Research Articles on MRPL12

1. knock-down of MRPL12 by RNA interference results in instability of POLRMT.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MRPL12 antibody

Products by Pathway	Pathway Diagram
Ribosome Pathway antibodies	Ribosome Pathway Diagram
Ribosome Pathway antibodies	Ribosome Pathway Diagram

Diseases associated with anti-MRPL12 antibody

Disease Name	Pubmed Publications
Anoxia Antibodies	>1 publications with MRPL12 and Anoxia
Death Antibodies	>1 publications with MRPL12 and Death

Organs/Tissues associated with anti-MRPL12 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with MRPL12 and Liver
Intestine Antibodies	>1 publications with MRPL12 and Intestine
Eye Antibodies	>1 publications with MRPL12 and Eye
Muscle Antibodies	>1 publications with MRPL12 and Muscle
Ovary Antibodies	>1 publications with MRPL12 and Ovary