Mouse Anti-ATP6V1B2 Monoclonal Antibody – Cat# MBS6221023

ATP6V1B2 Antibody – Mouse Monoclonal

Name: ATP6V1B2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6221023
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6221023

Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATP6V1B2, Monoclonal Antibody

Full Product Name

ATP6V1B2 (V-type Proton ATPase Subunit B, Brain Isoform, V-ATPase Subunit B 2, Endomembrane Proton Pump 58kD Subunit, HO57, Vacuolar Proton Pump Subunit B 2, ATP6B2, VPP3) (MaxLight 650)

Product Gene Name

anti-ATP6V1B2 antibody

Clonality

Monoclonal

Isotype

IgG2b,k

Clone Number

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human ATP6V1B2.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

56,501 Da

Immunogen

Full length recombinant corresponding to aa1-511 from human ATP6V1B2 (AAH03100) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH

Conjugate

MaxLight650

Product Categories/Family for anti-ATP6V1B2 antibody

Antibodies; Enzymes; ATPase

Applications Tested/Suitable for anti-ATP6V1B2 antibody

FLISA

Application Notes for anti-ATP6V1B2 antibody

Applications are based on unconjugated antibody.

Product References and Citations for anti-ATP6V1B2 antibody

1. Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: Correlation to lysosomal pH. Nilsson C, Roberg K, Grafstrom RC, Ollinger K.Head Neck. 2010 Sep;32(9):1185-94.

Other Notes

Small volumes of anti-ATP6V1B2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP6V1B2 purchase

MBS6221023 is an antibody targeting ATP6V1B2. Also known as ATP6V1B2 (V-type Proton ATPase Subunit B, Brain Isoform, V-ATPase Subunit B 2, Endomembrane Proton Pump 58kD Subunit, HO57, Vacuolar Proton Pump Subunit B 2, ATP6B2, VPP3) (MaxLight 650). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP6V1B2. It may not necessarily be applicable to this product.

NCBI GI #

13111864

NCBI GeneID

526

NCBI Accession #

BC003100

NCBI Related Accession #

AAH03100

UniProt Secondary Accession #

Q14544; Q15859; Q96IR0; B2R5Z3; D3DSQ5

UniProt Related Accession #

P21281

NCBI Official Full Name

Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, mRNA

NCBI Official Synonym Full Names

ATPase H+ transporting V1 subunit B2

NCBI Official Symbol

ATP6V1B2

NCBI Official Synonym Symbols

DOOD; HO57; VATB; VPP3; Vma2; ZLS2; ATP6B2; ATP6B1B2

Protein Family

V-type proton ATPase

NCBI Protein Information

V-type proton ATPase subunit B, brain isoform

NCBI Summary for ATP6V1B2

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]

Research Articles on ATP6V1B2

1. A missense mutation in ATP6V1B2 associated with Zimmermann-Laband syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ATP6V1B2 antibody

Products by Pathway	Pathway Diagram
Collecting Duct Acid Secretion Pathway antibodies	Collecting Duct Acid Secretion Pathway Diagram
Collecting Duct Acid Secretion Pathway antibodies	Collecting Duct Acid Secretion Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Insulin Receptor Recycling Pathway antibodies	Insulin Receptor Recycling Pathway Diagram
Iron Uptake And Transport Pathway antibodies	Iron Uptake And Transport Pathway Diagram
Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway antibodies	Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram

Diseases associated with anti-ATP6V1B2 antibody

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>2 publications with ATP6V1B2 and Mental Disorders
Nervous System Diseases Antibodies	>2 publications with ATP6V1B2 and Nervous System Diseases
Mood Disorders Antibodies	>1 publications with ATP6V1B2 and Mood Disorders
Epilepsy, Tonic-Clonic Antibodies	>1 publications with ATP6V1B2 and Epilepsy, Tonic-Clonic
Seizures Antibodies	>1 publications with ATP6V1B2 and Seizures
Brain Diseases Antibodies	>1 publications with ATP6V1B2 and Brain Diseases
Kidney Diseases Antibodies	>1 publications with ATP6V1B2 and Kidney Diseases
Depressive Disorder Antibodies	>1 publications with ATP6V1B2 and Depressive Disorder
Osteoarthritis Antibodies	>1 publications with ATP6V1B2 and Osteoarthritis