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Keratin 17 (KRT17) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6222867

The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life. Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin.… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Keratin 17 (KRT17), Monoclonal Antibody
Full Product Name
Keratin 17 (Keratin Type I Cytoskeletal 17, Keratin-17, K17, KRT17, 39.1, Cytokeratin-17, CK-17) (MaxLight 650)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2D4-1G9
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human Keratin 17.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
52KD
Immunogen
Full length recombinant protein corresponding to aa1-432 of human Keratin 17 (BC000159; AAH00159) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRIPNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR
Conjugate
MaxLight650

Product Categories/Family for anti-KRT17 antibody

Applications Tested/Suitable for anti-KRT17 antibody
FLISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-KRT17 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-KRT17 antibody

Western Blot detection against immunogen (73.26kD).
Mouse Anti-KRT17 Monoclonal Antibody – Cat# MBS6222867

Western Blot (WB) of anti-KRT17 antibody

Western Blot analysis of KRT17 expression in A-431 using 128772.
Mouse Anti-KRT17 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6222867

Immunoprecipitation (IP) of anti-KRT17 antibody

Immunoprecipitation of KRT17 transfected lysate using 128772 and Protein A Magnetic Bead, and immunoblotted with 128772.
Mouse Anti-KRT17 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS6222867

Immunohistochemistry (IHC) of anti-KRT17 antibody

Immunoperoxidase on formalin-fixed paraffin-embedded human tonsil using 128772 (3ug/ml).
Mouse Anti-KRT17 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6222867

Immunofluorescence (IF) of anti-KRT17 antibody

Immunofluorescence to KRT17 on HeLa cells using 128772 (25ug/ml).
Mouse Anti-KRT17 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6222867

Product References and Citations for anti-KRT17 antibody

1. Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. Turashvili G, Bouchal J, Baumforth K, Wei W, Dziechciarkova M, Ehrmann J, Klein J, Fridman E, Skarda J, Srovnal J, Hajduch M, Murray P, Kolar Z.BMC Cancer. 2007 Mar 27;7:55.

Other Notes

Small volumes of anti-KRT17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRT17 purchase

MBS6222867 is an antibody targeting KRT17. Also known as Keratin 17 (Keratin Type I Cytoskeletal 17, Keratin-17, K17, KRT17, 39.1, Cytokeratin-17, CK-17) (MaxLight 650). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT17. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens keratin 17, mRNA
NCBI Official Synonym Full Names
keratin 17
NCBI Official Symbol
KRT17
NCBI Official Synonym Symbols
PC; K17; PC2; 39.1; CK-17; PCHC1
Protein Family
NCBI Protein Information
keratin, type I cytoskeletal 17

NCBI Summary for KRT17

This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT17 antibody

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