Mouse Anti-POLR2C Monoclonal Antibody – Cat# MBS6223936

POLR2C Antibody – Mouse Monoclonal

Name: POLR2C Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6223936
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6223936

This protein is the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. It contains a cysteine rich region and exists as a heterodimer with another polymerase subunit. These two subunits form a… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

POLR2C, Monoclonal Antibody

Full Product Name

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 650)

Product Gene Name

anti-POLR2C antibody

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

1C11

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human POLR2C.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunogen

Full length recombinant corresponding to aa1-276 from human POLR2C (AAH28157) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKK

Conjugate

MaxLight650

Product Categories/Family for anti-POLR2C antibody

Antibodies; Enzymes; Polymerase

Applications Tested/Suitable for anti-POLR2C antibody

FLISA

Application Notes for anti-POLR2C antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-POLR2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POLR2C purchase

MBS6223936 is an antibody targeting POLR2C. Also known as POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 650). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for POLR2C. It may not necessarily be applicable to this product.

NCBI GI #

20380435

NCBI GeneID

5432

NCBI Accession #

BC028157

NCBI Related Accession #

AAH28157

UniProt Related Accession #

P19387

NCBI Official Full Name

Homo sapiens polymerase (RNA) II (DNA directed) polypeptide C, 33kDa, mRNA

NCBI Official Synonym Full Names

RNA polymerase II subunit C

NCBI Official Symbol

POLR2C

NCBI Official Synonym Symbols

RPB3; RPB31; hRPB33; hsRPB3

NCBI Protein Information

DNA-directed RNA polymerase II subunit RPB3

NCBI Summary for POLR2C

This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]

Research Articles on POLR2C

1. FUS low-complexicity phase separates to recruit RNA polymerase II C-terminal domain in vitro.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.