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Telomerase-Associated Protein 1 (TEP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS622636

MBS622636 is an antibody targeting TEP1. Also known as Telomerase-Associated Protein 1 (TEP1, P240, TLP1, TP1, Tp-1, TROVE1, VAULT2). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$915 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Telomerase-Associated Protein 1 (TEP1), Polyclonal Antibody
Full Product Name
Telomerase-Associated Protein 1 (TEP1, P240, TLP1, TP1, Tp-1, TROVE1, VAULT2)
Product Gene Name
Product Synonym Names
Anti -Telomerase-Associated Protein 1 (TEP1, P240, TLP1, TP1, Tp-1, TROVE1, VAULT2)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity
Recognizes Human Telomerase-associated Protein Tp-1 (TEP1). Species Crossreactivity: Human, Mouse, Rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
290,490 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (20833826..20881579, complement). Location: 14q11.2
OMIM
601686
3D Structure
ModBase 3D Structure for Q99973
Immunogen
Synthetic peptide, KLH-conjugated. Epitope: 20 amino acid peptide from near the amino terminus of human TP1.

Product Categories/Family for anti-TEP1 antibody

Applications Tested/Suitable for anti-TEP1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TEP1 antibody
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry: 5ug/ml

Immunohistochemistry (IHC) of anti-TEP1 antibody

TEP1 (5ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human breast, followed by biotinylated goat rabbit IgG secondary, alkaline phosphatase-streptavidin and chromogen.
Rabbit Anti-TEP1 Polyclonal Antibody – Cat# MBS622636

Immunohistochemistry (IHC) of anti-TEP1 antibody

TEP1 (5ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human skin, followed by biotinylated goat rabbit IgG secondary, alkaline phosphatase-streptavidin and chromogen.
Rabbit Anti-TEP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS622636

Other Notes

Small volumes of anti-TEP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TEP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
telomerase-associated protein 1
NCBI Official Synonym Full Names
telomerase-associated protein 1
NCBI Official Symbol
TEP1
NCBI Official Synonym Symbols
TP1; TLP1; p240; TROVE1; VAULT2
UniProt Protein Name
Telomerase protein component 1
UniProt Synonym Protein Names
Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog
UniProt Gene Name
TEP1
UniProt Synonym Gene Names
TLP1; TP1
UniProt Entry Name
TEP1_HUMAN
NCBI Protein Information
telomerase protein component 1; OTTHUMP00000028244; telomerase protein 1; p80 telomerase homolog; TROVE domain family, member 1

NCBI Summary for TEP1

This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. [provided by RefSeq]

UniProt Comments for TEP1

TEP1: Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: chromosome, telomeric region; nuclear matrix; telomerase holoenzyme complex; cytoplasm; ribonucleoprotein complex

Molecular Function: telomerase activity; RNA binding; ATP binding

Biological Process: RNA-dependent DNA replication; telomere maintenance via recombination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TEP1 antibody

 Reference Product  PubMed Publications
 TERT antibody  >25 publications with TEP1 and TERT
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