Goat Anti-STEAP1 Polyclonal Antibody – Cat# MBS622796

Detection of STEAP1A. Cell lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1.0ug/ml goat anti-hSTEAP1.

Six-Transmembrane Epithelial Antigen of the Prostate-1 (STEAP1) Antibody – Goat Polyclonal

Name: STEAP1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS622796
Price: 1080 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS622796

STEAP1 (six-transmembrane epithelial antigen of the prostate-1) is a 40kD protein (predicted) of the STEAP family of metalloreductases. It is expressed mainly at cell-cell junctions between prostate secretory epithelium, and upregulated in prostate and some… More details

$1080 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Six-transmembrane epithelial antigen of the prostate-1 (STEAP1), Polyclonal Antibody

Full Product Name

Six-transmembrane epithelial antigen of the prostate-1 (STEAP1, six transmembrane epithelial antigen of the prostate 1, Metalloreductase STEAP1, MGC19484, PRSS24, Six-transmembrane epithelial antigen of prostate 1, STEAP)

Product Gene Name

anti-STEAP1 antibody

Product Synonym Names

Anti -Six-transmembrane epithelial antigen of the prostate-1 (STEAP1, six transmembrane epithelial antigen of the prostate 1, Metalloreductase STEAP1, MGC19484, PRSS24, Six-transmembrane epithelial antigen of prostate 1, STEAP)

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder in 0.2um sterile-filtered solution, PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human STEAP1.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

39,851 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (89783689..89794141). Location: 7q21

OMIM

604415

3D Structure

ModBase 3D Structure for Q9UHE8

Immunogen

Human STEAP1 aa1- 72; Q9UHE8.

Product Categories/Family for anti-STEAP1 antibody

Antibodies; Abs to Cancer Markers

Applications Tested/Suitable for anti-STEAP1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-STEAP1 antibody

Dilution: ELISA: 0.5-1.0ug/ml
Western Blot: 1.0ug/ml

Other Notes

Small volumes of anti-STEAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STEAP1 purchase

MBS622796 is an antibody targeting STEAP1. Also known as Six-transmembrane epithelial antigen of the prostate-1 (STEAP1, six transmembrane epithelial antigen of the prostate 1, Metalloreductase STEAP1, MGC19484, PRSS24, Six-transmembrane epithelial antigen of prostate 1, STEAP). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for STEAP1. It may not necessarily be applicable to this product.

NCBI GI #

15080037

NCBI GeneID

26872

UniProt Primary Accession #

Q9UHE8

UniProt Secondary Accession #

O95034; A4D1E0

UniProt Related Accession #

Q9UHE8

NCBI Official Full Name

Six transmembrane epithelial antigen of the prostate 1

NCBI Official Synonym Full Names

six transmembrane epithelial antigen of the prostate 1

NCBI Official Symbol

STEAP1

NCBI Official Synonym Symbols

STEAP; PRSS24; MGC19484

UniProt Protein Name

Metalloreductase STEAP1

UniProt Synonym Protein Names

Six-transmembrane epithelial antigen of prostate 1

Protein Family

Metalloreductase

UniProt Gene Name

STEAP1

UniProt Synonym Gene Names

PRSS24; STEAP

UniProt Entry Name

STEA1_HUMAN

NCBI Protein Information

metalloreductase STEAP1; OTTHUMP00000024624; six-transmembrane epithelial antigen of prostate 1

NCBI Summary for STEAP1

This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq]

UniProt Comments for STEAP1

STEAP1: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family.

Protein type: Membrane protein, integral; Oxidoreductase; EC 1.16.1.-; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 7q21

Cellular Component: membrane; integral to plasma membrane; plasma membrane; endosome membrane; intercellular junction

Molecular Function: transporter activity; channel activity; metal ion binding; oxidoreductase activity

Biological Process: iron ion homeostasis; ion transport; transmembrane transport

Research Articles on STEAP1

1. Data suggest that zoledronic acid may affect cancer cells also by targeting the gene expression of STEAP.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STEAP1 antibody

Products by Pathway	Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram

Diseases associated with anti-STEAP1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>18 publications with STEAP1 and Neoplasms
Prostatic Neoplasms Antibodies	>12 publications with STEAP1 and Prostatic Neoplasms
Neoplasms, Experimental Antibodies	>3 publications with STEAP1 and Neoplasms, Experimental
Lung Neoplasms Antibodies	>2 publications with STEAP1 and Lung Neoplasms
Kidney Neoplasms Antibodies	>2 publications with STEAP1 and Kidney Neoplasms
Urinary Bladder Neoplasms Antibodies	>2 publications with STEAP1 and Urinary Bladder Neoplasms
Adenocarcinoma Antibodies	>2 publications with STEAP1 and Adenocarcinoma
Breast Neoplasms Antibodies	>2 publications with STEAP1 and Breast Neoplasms
Lung Diseases Antibodies	>2 publications with STEAP1 and Lung Diseases
Melanoma Antibodies	>2 publications with STEAP1 and Melanoma

Organs/Tissues associated with anti-STEAP1 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>22 publications with STEAP1 and Prostate
Bone Antibodies	>5 publications with STEAP1 and Bone
Lung Antibodies	>2 publications with STEAP1 and Lung
Pancreas Antibodies	>1 publications with STEAP1 and Pancreas
Mammary Gland Antibodies	>1 publications with STEAP1 and Mammary Gland
Embryonic Tissue Antibodies	>1 publications with STEAP1 and Embryonic Tissue