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p130CAS Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS622804

p130Cas (protein 130kD Crk-associated substrate; also BCAR1) is a cytoplasmic member of the CAS family of proteins. Although its predicted MW is 93kD, it runs anomalously at 105-130kD in SDS-PAGE. It is found in a wide variety of cell types. p130Cas is… More details

$1065 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
p130Cas, Polyclonal Antibody
Full Product Name
p130Cas (Cas for Crk-associated substrate, BCAR1, K-associated Substrate, Breast Cancer anti-estrogen Resistance 1 Protein)
Product Gene Name
Product Synonym Names
Anti -p130Cas (Cas for Crk-associated substrate, BCAR1, K-associated Substrate, Breast Cancer anti-estrogen Resistance 1 Protein)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes endogenous human p130Cas at 105-130kD. Species Crossreactivity: mouse, rat.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, sterile 40-50% glycerol, 0.02% sodium azide, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
85,622 Da
Chromosome Location
Chromosome: 3L; NT_037436.3 (150857..174524). Location: 61B1-61B2
3D Structure
ModBase 3D Structure for Q7KVE5
Immunogen
E. coli-derived recombinant human p130Cas (aa66-412).

Product Categories/Family for anti-p130CAS antibody

Applications Tested/Suitable for anti-p130CAS antibody
Western Blot (WB)
Application Notes for anti-p130CAS antibody
Suitable for use in Western Blot.
Dilution: Western Blot: 1ug/ml

SDS-Page of anti-p130CAS antibody

Detection of p130Cas with MBS622804. Lysates from human HeLa, mouse NIH3T3, and rat L6 cells were resolved by SDS-PAGE. Following electrophoresis, proteins were transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml sheep anti-p130Cas.
Sheep Anti-p130CAS Polyclonal Antibody – Cat# MBS622804

Other Notes

Small volumes of anti-p130CAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for p130CAS purchase

MBS622804 is an antibody targeting p130CAS. Also known as p130Cas (Cas for Crk-associated substrate, BCAR1, K-associated Substrate, Breast Cancer anti-estrogen Resistance 1 Protein). Reactive in Human, Mouse, Rat. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for p130CAS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
p130CAS, isoform G
NCBI Official Symbol
p130CAS
NCBI Official Synonym Symbols
CG1212; CT1293; Dcas; DCas; DmelCG1212
UniProt Protein Name
Crk-associated substrate
UniProt Gene Name
p130CAS
UniProt Entry Name
Q7KVE5_DROME
NCBI Protein Information
CG1212 gene product from transcript CG1212-RA; p130CAS, isoform A; CG1212-PA; p130CAS-PA; p130CAS, isoform D; CG1212-PD; p130CAS-PD; p130CAS, isoform G; CG1212-PG; p130CAS-PG; p130CAS, isoform B; CG1212-PB; p130CAS-PB; p130CAS, isoform F; CG1212-PF; p130CAS-PF; p130CAS, isoform E; CG1212-PE; p130CAS-PE

UniProt Comments for p130CAS

Sequence similarities: Contains 1 SH3 domain. RuleBase RU003338

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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