Dopamine Receptor D(1a) (DRD1A) Antibody – Rabbit Polyclonal

DRD1: a G-protein coupled receptor.One of the five types (D1 to D5) of receptors for dopamine. The most abundant dopamine receptor in the central nervous system. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Interacts with calcyon.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; cell; integral to plasma membrane; dendrite; dendritic spine; integral to membrane; caveola; cell soma; membrane; axon; plasma membrane; intracellular; nerve terminal; dendritic shaft; nucleus

Molecular Function: angiotensin receptor binding; G-protein coupled receptor activity; protein binding; dopamine receptor activity; protein heterodimerization activity; dopamine binding; protein complex binding; G-protein alpha-subunit binding; drug binding; dopamine D1 receptor-like receptor activity; D3 dopamine receptor binding; protein phosphatase binding; ATPase binding; receptor binding

Biological Process: response to nicotine; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); prepulse inhibition; thermoregulation; response to organic cyclic substance; G-protein signaling, adenylate cyclase activating pathway; adult walking behavior; protein import into nucleus; conditioned taste aversion; positive regulation of cAMP biosynthetic process; positive regulation of adenylate cyclase activity; phosphatidylinositol metabolic process; response to food; response to drug; phosphatidylinositol catabolic process; dopamine transport; dentate gyrus development; cerebral cortex GABAergic interneuron migration; adenylate cyclase activation; mating behavior; transmission of nerve impulse; social behavior; response to amino acid stimulus; response to organic nitrogen; G-protein signaling, coupled to cyclic nucleotide second messenger; response to ethanol; cellular response to insulin stimulus; response to steroid hormone stimulus; regulation of vasoconstriction; glucose import; operant conditioning; dopamine receptor signaling pathway; negative regulation of protein kinase activity; response to activity; positive regulation of membrane potential; regulation of ion transport; regulation of long-term neuronal synaptic plasticity; synaptic transmission, dopaminergic; peristalsis; startle response; behavioral fear response; negative regulation of circadian sleep/wake cycle, sleep; generation of action potential; response to morphine; locomotory behavior; orbitofrontal cortex development; vasodilation; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; intracellular protein transport; synaptic transmission; synaptogenesis; muscle contraction; behavioral response to cocaine; visual learning; feeding behavior; negative regulation of cell migration; associative learning; dopamine receptor, adenylate cyclase activating pathway; grooming behavior; response to retinoic acid; striatum development; maternal behavior; regulation of dopamine metabolic process; response to amphetamine; hippocampus development; calcium-mediated signaling; learning; response to cocaine; astrocyte development; memory; G-protein coupled receptor protein signaling pathway; habituation; sensitization; positive regulation of release of sequestered calcium ion into cytosol; dopamine receptor, phospholipase C activating pathway; positive regulation of cell migration