Goat Anti-AVPR1B Polyclonal Antibody – Cat# MBS623221

EB08785 (0.5µg/ml) staining of Human Amygdala lysate (35µg protein in RIPA buffer) in lane A and EB08786 (0.05µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer) in lane B . Primary incubation was 1 hour. Detected by chemiluminescence.

AVPR1B Antibody – Goat Polyclonal

Name: AVPR1B Antibody; Polyclonal; Goat; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS623221
Price: 660 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623221

$660 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AVPR1B, Polyclonal Antibody

Full Product Name

AVPR1B (AAvpr1b, Arginine Vasopressin Receptor 1B, AVPR3, Antidiuretic Hormone Receptor 1B, Arginine Vasopressin Receptor 3, Pituitary Vasopressin Receptor 3, Vasopressin V1B Receptor; AVPR3, V3/V1b, VIBR, VPR; V3/V1b pituitary vasopressin receptor, VPR3)

Product Gene Name

anti-AVPR1B antibody

Product Synonym Names

Anti -AVPR1B (AAvpr1b, Arginine Vasopressin Receptor 1B, AVPR3, Antidiuretic Hormone Receptor 1B, Arginine Vasopressin Receptor 3, Pituitary Vasopressin Receptor 3, Vasopressin V1B Receptor; AVPR3, V3/V1b, VIBR, VPR; V3/V1b pituitary vasopressin receptor, VPR3)

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Rat

Form/Format

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

Purity/Purification

Affinity Purified
Purified by affinity chromatography.

Specificity

Recognizes rat AVPR1B. Sequence Homology: mouse.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

46,971 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (206224283..206231482). Location: 1q32

OMIM

600264

3D Structure

ModBase 3D Structure for P47901

Immunogen

Synthetic peptide corresponding to C-KPAGSLKDLEQVD, from the internal region (near C-Terminus) of AVPR1B (NP_036054.1).

Product Categories/Family for anti-AVPR1B antibody

Antibodies; Abs to Receptors

Applications Tested/Suitable for anti-AVPR1B antibody

Western Blot (WB)

Application Notes for anti-AVPR1B antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:32,000

Other Notes

Small volumes of anti-AVPR1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AVPR1B purchase

MBS623221 is an antibody targeting AVPR1B. Also known as AVPR1B (AAvpr1b, Arginine Vasopressin Receptor 1B, AVPR3, Antidiuretic Hormone Receptor 1B, Arginine Vasopressin Receptor 3, Pituitary Vasopressin Receptor 3, Vasopressin V1B Receptor; AVPR3, V3/V1b, VIBR, VPR; V3/V1b pituitary vasopressin receptor, VPR3). Reactive in Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for AVPR1B. It may not necessarily be applicable to this product.

NCBI GI #

74418840

NCBI GeneID

553

UniProt Primary Accession #

P47901

UniProt Secondary Accession #

Q5TZ00; B0M0J6

UniProt Related Accession #

P47901

NCBI Official Full Name

arginine vasopressin receptor 1B

NCBI Official Synonym Full Names

arginine vasopressin receptor 1B

NCBI Official Symbol

AVPR1B

NCBI Official Synonym Symbols

AVPR3

UniProt Protein Name

Vasopressin V1b receptor

UniProt Synonym Protein Names

AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor

Protein Family

Vasopressin V1b receptor

UniProt Gene Name

AVPR1B

UniProt Synonym Gene Names

AVPR3; VPR3

UniProt Entry Name

V1BR_HUMAN

NCBI Protein Information

vasopressin V1b receptor; V1bR; AVPR V3; AVPR V1b; OTTHUMP00000034344; vasopressin V3 receptor; arginine vasopressin receptor 3; antidiuretic hormone receptor 1B; pituitary vasopressin receptor 3

NCBI Summary for AVPR1B

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq]

UniProt Comments for AVPR1B

AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: integral to plasma membrane; plasma membrane; endosome

Molecular Function: protein kinase C binding; peptide binding; vasopressin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; regulation of systemic arterial blood pressure by vasopressin; phospholipase C activation; positive regulation of vasoconstriction; cellular response to hormone stimulus

Research Articles on AVPR1B

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AVPR1B antibody

Reference Product	PubMed Publications
AVP antibody	>2221 publications with AVPR1B and AVP
GRK5 antibody	>3 publications with AVPR1B and GRK5

Pathways associated with anti-AVPR1B antibody

Products by Pathway	Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram

Diseases associated with anti-AVPR1B antibody

Disease Name	Pubmed Publications
Female Urogenital Diseases Antibodies	>462 publications with AVPR1B and Female Urogenital Diseases
Inflammation Antibodies	>83 publications with AVPR1B and Inflammation
Lung Neoplasms Antibodies	>38 publications with AVPR1B and Lung Neoplasms
Neoplasms, Hormone-Dependent Antibodies	>16 publications with AVPR1B and Neoplasms, Hormone-Dependent
Liver Cirrhosis, Experimental Antibodies	>15 publications with AVPR1B and Liver Cirrhosis, Experimental
Breast Neoplasms Antibodies	>14 publications with AVPR1B and Breast Neoplasms
Acidosis Antibodies	>13 publications with AVPR1B and Acidosis
Liver Neoplasms Antibodies	>13 publications with AVPR1B and Liver Neoplasms
Mammary Neoplasms, Animal Antibodies	>10 publications with AVPR1B and Mammary Neoplasms, Animal
Mammary Neoplasms, Experimental Antibodies	>10 publications with AVPR1B and Mammary Neoplasms, Experimental

Organs/Tissues associated with anti-AVPR1B antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2359 publications with AVPR1B and Brain
Mixed Antibodies	>63 publications with AVPR1B and Mixed