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Scavenger Receptor, Cysteine Rich Domain (SRCRB4D) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623326

SRCRB4D (Scavenger receptor cysteine-rich domain group B four B-type domain containing) is a 56 kD (predicted), secreted member of the SRCR superfamily. It is widely expressed and likely plays some role in innate immunity. Mature human SRCRB4D is 528aa in… More details

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Product Overview

Online Datasheet in PDF
Product Name
Scavenger Receptor, Cysteine Rich Domain (SRCRB4D), Polyclonal Antibody
Full Product Name
Scavenger Receptor, Cysteine Rich Domain (SRCRB4D, group B (4 domains) S4D-SRCRB, SRCRB-S4D)
Product Gene Name
Product Synonym Names
Anti -Scavenger Receptor, Cysteine Rich Domain (SRCRB4D, group B (4 domains) S4D-SRCRB, SRCRB-S4D)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes human SRCRB4D.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
60,819 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (76018646..76039012, complement). Location: 7q11.23
OMIM
607639
3D Structure
ModBase 3D Structure for Q8WTU2
Immunogen
CHO cell-derived recombinant human SRCRB4D isoform 1.
Applications Tested/Suitable for anti-SRCRB4D antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SRCRB4D antibody
Dilution: Direct ELISA: 0.5-1.0ug/ml
Western Blot: 1.0ug/ml

SDS-Page of anti-SRCRB4D antibody

Detection of SRCRB4D. Cell lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with MBS623326 (1ug/ml)
Sheep Anti-SRCRB4D Polyclonal Antibody – Cat# MBS623326

Other Notes

Small volumes of anti-SRCRB4D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRCRB4D purchase

MBS623326 is an antibody targeting SRCRB4D. Also known as Scavenger Receptor, Cysteine Rich Domain (SRCRB4D, group B (4 domains) S4D-SRCRB, SRCRB-S4D). Reactive in Human. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for SRCRB4D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
scavenger receptor cysteine rich domain containing, group B (4 domains)
NCBI Official Synonym Full Names
scavenger receptor cysteine rich domain containing, group B (4 domains)
NCBI Official Symbol
SRCRB4D
NCBI Official Synonym Symbols
SSC4D; S4D-SRCRB; SRCRB-S4D
UniProt Protein Name
Scavenger receptor cysteine-rich domain-containing group B protein
UniProt Synonym Protein Names
S4-SRCRB
UniProt Gene Name
SRCRB4D
UniProt Entry Name
SRB4D_HUMAN
NCBI Protein Information
scavenger receptor cysteine-rich domain-containing group B protein; S4-SRCRB; OTTHUMP00000161135; scavenger receptor cysteine-rich protein SRCRB-S4D

NCBI Summary for SRCRB4D

The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.[supplied by OMIM]
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UniProt Comments for SRCRB4D

SRCRB4D: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: membrane

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SRCRB4D antibody

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