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Procalcitonin (S100A9) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623342

Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin… More details

$1015 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Procalcitonin (S100a9), Polyclonal Antibody
Full Product Name
Procalcitonin (PCT)
Product Gene Name
anti-S100a9 antibody
Product Synonym Names
Anti -Procalcitonin (PCT)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human
Form/Format
Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
Purity/Purification
Purified
Purified
Specificity
Recognizes human Procalctonin.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
13,145 Da
Chromosome Location
Chromosome: 2; NC_005101.3 (209531412..209534093, complement). Location: 2q34
3D Structure
ModBase 3D Structure for P50116
Immunogen
Recombinant corresponding to aa3-116 from human procalcitonin, fused to 6x His-tag at N-terminal, expressed in E. coli.

Product Categories/Family for anti-S100a9 antibody

Antibodies; Abs to Calcitonin
Applications Tested/Suitable for anti-S100a9 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Gel Shift Assay (GS/EMSA)
Application Notes for anti-S100a9 antibody
Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays.

Other Notes

Small volumes of anti-S100a9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S100a9 purchase

MBS623342 is an antibody targeting S100a9. Also known as Procalcitonin (PCT). Reactive in Human. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for S100a9. It may not necessarily be applicable to this product.

NCBI GI #
16758364
NCBI GeneID
94195
NCBI Accession #
NP_446039.1
UniProt Primary Accession #
P50116
UniProt Secondary Accession #
Q761U7
UniProt Related Accession #
P50116
GenBank Nucleotide #
NM_053587.1
NCBI Official Full Name
protein S100-A9
NCBI Official Synonym Full Names
S100 calcium binding protein A9
NCBI Official Symbol
S100a9
NCBI Official Synonym Symbols
Mrp14
UniProt Protein Name
Protein S100-A9
UniProt Synonym Protein Names
Calgranulin-B; Migration inhibitory factor-related protein 14; MRP-14; p14; Myeloid-related protein 14; S100 calcium-binding protein A9
Protein Family
Protein
UniProt Gene Name
S100a9
UniProt Synonym Gene Names
Mrp14; MRP-14; p14
UniProt Entry Name
S10A9_RAT
NCBI Protein Information
protein S100-A9; p14; MRP-14; calgranulin-B; myeloid-related protein 14; intracellular calcium-binding protein (MRP14); migration inhibitory factor-related protein 14; S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A9 (calgranulin B)

NCBI Summary for S100a9

calcium binding protein that may be associated with acute inflammatory processes [RGD, Feb 2006]

UniProt Comments for S100a9

S100A9: a calcium-binding regulatory protein of the S-100 family expressed by macrophages in acutely inflammated tissues and in chronic inflammations. May be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or induced during dermatoses. May interact with components of the intermediate filaments in monocytes and epithelial cells. Interacts with CEACAM3 in a calcium-dependent manner.

Protein type: Calcium-binding; Motility/polarity/chemotaxis; Cytoskeletal

Cellular Component: extracellular space; cytoskeleton; cytoplasm; plasma membrane; nucleus

Molecular Function: arachidonic acid binding; antioxidant activity; RAGE receptor binding; zinc ion binding; microtubule binding; calcium ion binding

Biological Process: caspase activation; neutrophil chemotaxis; chronic inflammatory response; leukocyte chemotaxis; response to lipopolysaccharide; positive regulation of peptide secretion; leukocyte migration during inflammatory response; response to ethanol; response to zinc ion; actin cytoskeleton reorganization; autophagy; innate immune response; regulation of integrin biosynthetic process; positive regulation of inflammatory response
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Research Articles on S100a9

1. Data indicate that serum calprotectin levels correlated with serum levels of TNF-alpha and IL6 in TNBS colitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-S100a9 antibody

 Reference Product  PubMed Publications
 S100a8 antibody  >630 publications with S100a9 and S100a8
 Tlr4 antibody  >36 publications with S100a9 and Tlr4
 Cxcl1 antibody  >19 publications with S100a9 and Cxcl1
 Lcn2 antibody  >10 publications with S100a9 and Lcn2
 Il1b antibody  >9 publications with S100a9 and Il1b
 Mmp9 antibody  >8 publications with S100a9 and Mmp9
 Il6 antibody  >7 publications with S100a9 and Il6
 Hmgb1 antibody  >6 publications with S100a9 and Hmgb1
 Anxa1 antibody  >1 publications with S100a9 and Anxa1

Diseases associated with anti-S100a9 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >320 publications with S100a9 and Inflammation
 Neoplasms Antibodies  >190 publications with S100a9 and Neoplasms
 Skin Diseases Antibodies  >98 publications with S100a9 and Skin Diseases
 Disease Models, Animal Antibodies  >71 publications with S100a9 and Disease Models, Animal
 Nervous System Diseases Antibodies  >64 publications with S100a9 and Nervous System Diseases
 Necrosis Antibodies  >61 publications with S100a9 and Necrosis
 Cardiovascular Diseases Antibodies  >58 publications with S100a9 and Cardiovascular Diseases
 Carcinoma, Squamous Cell Antibodies  >41 publications with S100a9 and Carcinoma, Squamous Cell
 Fibrosis Antibodies  >38 publications with S100a9 and Fibrosis
 Brain Diseases Antibodies  >34 publications with S100a9 and Brain Diseases

Organs/Tissues associated with anti-S100a9 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >38 publications with S100a9 and Liver
 Heart Antibodies  >25 publications with S100a9 and Heart
 Connective Tissue Antibodies  >18 publications with S100a9 and Connective Tissue
 Eye Antibodies  >14 publications with S100a9 and Eye
 Embryonic Tissue Antibodies  >13 publications with S100a9 and Embryonic Tissue
 Placenta Antibodies  >4 publications with S100a9 and Placenta
 Dorsal Root Ganglion Antibodies  >4 publications with S100a9 and Dorsal Root Ganglion
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