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CRABP2 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623365

The cellular retinoic acid-binding protein II (CRABP-II) is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is… More details

$755 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRABP2, Recombinant Protein
Full Product Name
CRABP2, Recombinant, Human (CRABP-2, CRABPII, CRABP-II, Cellular Retinoic Acid-Binding Protein 2, RBP6, Retinoic Acid Binding ProCtein 6)
Product Synonym Names
Anti -CRABP2, Recombinant, Human (CRABP-2, CRABPII, CRABP-II, Cellular Retinoic Acid-Binding Protein 2, RBP6, Retinoic Acid Binding ProCtein 6)
Sequence
MPNFSGNWKI IRSENFEELL KVLGVNVMLR KIAVAAASKP AVEIKQEGDT
FYIKTS TTVR TTEINFKVGE EFEEQTVDGR PCKSLVKWES ENKMVCEQKL
LKGEGP KTSW TRELTNDGEL ILTMTADDVV CTRVYVRE
Form/Format
Supplied as a liquid in Liquid in 20 mM Tris pH 8.0, 20% glycerol.
Purity/Purification
> 95% by SDS PAGE
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
15.6kD (138 aa)
Chromosome Location
Chromosome: 1; NC_000001.10 (156669403..156675375, complement). Location: 1q21.3
OMIM
180231
3D Structure
ModBase 3D Structure for P29373
Applications Tested/Suitable for CRABP2 recombinant protein
ELISA (EL/EIA)
Application Notes for CRABP2 recombinant protein
Suitable for use in ELISA.

Other Notes

Small volumes of CRABP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRABP2 purchase

MBS623365 is a recombinant protein targeting CRABP2. Also known as CRABP2, Recombinant, Human (CRABP-2, CRABPII, CRABP-II, Cellular Retinoic Acid-Binding Protein 2, RBP6, Retinoic Acid Binding ProCtein 6).

Additional Details

NCBI/Uniprot data below describe general gene information for CRABP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cellular retinoic acid-binding protein 2
NCBI Official Synonym Full Names
cellular retinoic acid binding protein 2
NCBI Official Symbol
CRABP2
NCBI Official Synonym Symbols
RBP6; CRABP-II
UniProt Protein Name
Cellular retinoic acid-binding protein 2
UniProt Synonym Protein Names
Cellular retinoic acid-binding protein II
UniProt Gene Name
CRABP2
UniProt Entry Name
RABP2_HUMAN
NCBI Protein Information
cellular retinoic acid-binding protein 2; OTTHUMP00000038730; OTTHUMP00000038732; cellular retinoic acid-binding protein II

NCBI Summary for CRABP2

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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UniProt Comments for CRABP2

CRABP2: Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; endoplasmic reticulum; cytoplasm; cytosol

Molecular Function: retinoid binding; retinoic acid binding; transporter activity; retinol binding; retinal binding

Biological Process: embryonic forelimb morphogenesis; epidermis development; regulation of transcription, DNA-dependent; retinoic acid metabolic process; signal transduction; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CRABP2 recombinant protein

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