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TRIP13 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623413

TRIP13 specifically interacts with the ligand binding domain of the thyroid receptor (TR). This interaction does not require the presence of thyroid hormone for its interaction. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRIP13, Polyclonal Antibody
Full Product Name
TRIP13, NT (Thyroid Receptor-interacting Protein 13, Thyroid Hormone Receptor Interactor 13, TR-interacting Protein 13, TRIP-13, Human Papillomavirus Type 16 E1 Protein-binding Protein, HPV16 E1 Protein-binding Protein, 16E1-BP)
Product Gene Name
anti-TRIP13 antibody
Product Synonym Names
Anti -TRIP13, NT (Thyroid Receptor-interacting Protein 13, Thyroid Hormone Receptor Interactor 13, TR-interacting Protein 13, TRIP-13, Human Papillomavirus Type 16 E1 Protein-binding Protein, HPV16 E1 Protein-binding Protein, 16E1-BP)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human TRIP13.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
48,551 Da
OMIM
604507
3D Structure
ModBase 3D Structure for Q15645
Immunogen
Synthetic peptide selected from the N-terminal region of human TRIP13 (KLH).

Product Categories/Family for anti-TRIP13 antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-TRIP13 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-TRIP13 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100

Western Blot (WB) of anti-TRIP13 antibody

Western blot analysis of TRIP13 Antibody (N-term) in K562, Hela, 293 cell line lysates (35ug/lane). TRIP13 (arrow) was detected using the purified Pab.
Rabbit Anti-TRIP13 Polyclonal Antibody – Cat# MBS623413

Immunohistochemistry (IHC) of anti-TRIP13 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with NRP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-TRIP13 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS623413

Flow Cytometry (FC/FACS) of anti-TRIP13 antibody

TRIP13 Antibody (N-term) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-TRIP13 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS623413

Western Blot (WB) of anti-TRIP13 antibody

Western blot analysis of TRIP13 (arrow) using rabbit polyclonal TRIP13 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TRIP13 gene.
Rabbit Anti-TRIP13 Polyclonal Antibody, Western Blot (WB) – Cat# MBS623413

Other Notes

Small volumes of anti-TRIP13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIP13 purchase

MBS623413 is an antibody targeting TRIP13. Also known as TRIP13, NT (Thyroid Receptor-interacting Protein 13, Thyroid Hormone Receptor Interactor 13, TR-interacting Protein 13, TRIP-13, Human Papillomavirus Type 16 E1 Protein-binding Protein, HPV16 E1 Protein-binding Protein, 16E1-BP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIP13. It may not necessarily be applicable to this product.

NCBI GI #
48145605
UniProt Primary Accession #
Q15645
UniProt Secondary Accession #
O15324; C9K0T3; D3DTC0
NCBI Official Full Name
TRIP13
UniProt Protein Name
Pachytene checkpoint protein 2 homolog
UniProt Synonym Protein Names
Human papillomavirus type 16 E1 protein-binding protein; 16E1-BP; HPV16 E1 protein-binding protein; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13
UniProt Gene Name
TRIP13
UniProt Synonym Gene Names
PCH2
UniProt Entry Name
PCH2_HUMAN

UniProt Comments for TRIP13

TRIP13: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Belongs to the AAA ATPase family. PCH2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 5p15.33

Cellular Component: male germ cell nucleus; nucleus

Molecular Function: identical protein binding; protein binding; transcription cofactor activity; ATP binding

Biological Process: transcription from RNA polymerase II promoter; oogenesis; synaptonemal complex assembly; male meiosis I; double-strand break repair; meiotic recombination; spermatogenesis; oocyte maturation; spermatid development; female meiosis I
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRIP13 antibody

 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with TRIP13 and FLNA

Pathways associated with anti-TRIP13 antibody

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram

Diseases associated with anti-TRIP13 antibody

 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >1 publications with TRIP13 and Infertility, Male
 Carcinoma, Non-Small-Cell Lung Antibodies  >1 publications with TRIP13 and Carcinoma, Non-Small-Cell Lung
 Infertility, Female Antibodies  >1 publications with TRIP13 and Infertility, Female
 Carcinoma, Small Cell Antibodies  >1 publications with TRIP13 and Carcinoma, Small Cell
 Carcinoma in Situ Antibodies  >1 publications with TRIP13 and Carcinoma in Situ
 Small Cell Lung Carcinoma Antibodies  >1 publications with TRIP13 and Small Cell Lung Carcinoma
 Neoplasms Antibodies  >1 publications with TRIP13 and Neoplasms
 Carcinoma Antibodies  >1 publications with TRIP13 and Carcinoma
 Lung Neoplasms Antibodies  >1 publications with TRIP13 and Lung Neoplasms

Organs/Tissues associated with anti-TRIP13 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >1 publications with TRIP13 and Prostate
 Skin Antibodies  >1 publications with TRIP13 and Skin
 Ovary Antibodies  >1 publications with TRIP13 and Ovary
 Lung Antibodies  >1 publications with TRIP13 and Lung
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