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PDAP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623419

Human PDAP1 encodes a deduced 181aa protein expressed in all tissues test with the exception of liver, most abundantly in brain. PDAP1 enhances PDGFA-stimulated cell growth in mouse fibroblasts, but inhibits the mitogenic effect of PDGFB. The binding between… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PDAP1, Polyclonal Antibody
Full Product Name
PDAP1, CT (28kD Heat-and Acid-stable Phosphoprotein, PDGF-associated Protein, PAP, PDGFA-associated Protein 1, PAP1, HASPP28)
Product Gene Name
Product Synonym Names
Anti -PDAP1, CT (28kD Heat-and Acid-stable Phosphoprotein, PDGF-associated Protein, PAP, PDGFA-associated Protein 1, PAP1, HASPP28)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human PDAP1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
20,630 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (98992589..99006292, complement). Location: 7q22.1
OMIM
607075
3D Structure
ModBase 3D Structure for Q13442
Immunogen
Synthetic peptide selected from the C-terminal region of human PDAP1 (KLH).
Applications Tested/Suitable for anti-PDAP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-PDAP1 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-PDAP1 antibody

The anti-PDAP1 Antibody (C-term) is used in Western blot to detect PDAP1 in HL60 lysate.
Rabbit Anti-PDAP1 Polyclonal Antibody – Cat# MBS623419

Western Blot (WB) of anti-PDAP1 antibody

Western blot analysis of PDAP1(arrow) using rabbit polyclonal PDAP1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDAP1 gene (Lane 2) (Origene Technologies).
Rabbit Anti-PDAP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS623419

Other Notes

Small volumes of anti-PDAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDAP1 purchase

MBS623419 is an antibody targeting PDAP1. Also known as PDAP1, CT (28kD Heat-and Acid-stable Phosphoprotein, PDGF-associated Protein, PAP, PDGFA-associated Protein 1, PAP1, HASPP28). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
PDGFA associated protein 1, isoform CRA_b
NCBI Official Synonym Full Names
PDGFA associated protein 1
NCBI Official Symbol
PDAP1
NCBI Official Synonym Symbols
PAP; PAP1; HASPP28
UniProt Protein Name
28 kDa heat- and acid-stable phosphoprotein
UniProt Synonym Protein Names
PDGF-associated protein; PAP; PDGFA-associated protein 1
UniProt Gene Name
PDAP1
UniProt Synonym Gene Names
HASPP28
UniProt Entry Name
HAP28_HUMAN
NCBI Protein Information
28 kDa heat- and acid-stable phosphoprotein; OTTHUMP00000206311; PDGF-associated protein

NCBI Summary for PDAP1

The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq]

UniProt Comments for PDAP1

PDAP1: Enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. Belongs to the PDAP1 family.

Chromosomal Location of Human Ortholog: 7q22.1

Biological Process: cell proliferation; signal transduction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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