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Small G Protein Signaling Modulator 3 (SGSM3) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623535

MBS623535 is an antibody targeting SGSM3. Also known as SGSM3, Small G Protein Signaling Modulator 3, (RUTBC3). Reactive in Human. Host: Goat. More details

$835 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SGSM3, Small G Protein Signaling Modulator 3, Polyclonal Antibody
Full Product Name
SGSM3, Small G Protein Signaling Modulator 3, (RUTBC3)
Product Gene Name
Product Synonym Names
Anti -SGSM3, Small G Protein Signaling Modulator 3, (RUTBC3)
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by peptide affinity chromatography.
Specificity
Recognizes human SGSM3. Species sequence homology: mouse, rat, canine.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
85,354 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (40766595..40806293). Location: 22q13.1-q13.2
OMIM
610440
3D Structure
ModBase 3D Structure for Q96HU1
Immunogen
Synthetic peptide corresponding to RDHENYVACSRSHRR, from the internal region of human SGSM3 (NP_056520.2).

Product Categories/Family for anti-SGSM3 antibody

Applications Tested/Suitable for anti-SGSM3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SGSM3 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Peptide ELISA Titer: 1:4000
Western Blot: 2-3ug/ml detects ~85kD band observed in lysates of Human Lung carcinoma cell line A549 (calculated MW of 85.4kD according to NP_056520.2).

Chemiluminescence of anti-SGSM3 antibody

MBS623535 (2µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SGSM3 Polyclonal Antibody – Cat# MBS623535

Other Notes

Small volumes of anti-SGSM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SGSM3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
small G protein signaling modulator 3
NCBI Official Synonym Full Names
small G protein signaling modulator 3
NCBI Official Symbol
SGSM3
NCBI Official Synonym Symbols
MAP; RUSC3; RUTBC3; DKFZp761D051
UniProt Protein Name
Small G protein signaling modulator 3
UniProt Synonym Protein Names
Merlin-associated protein; RUN and TBC1 domain-containing protein 3; Rab-GTPase-activating protein-like protein
UniProt Gene Name
SGSM3
UniProt Synonym Gene Names
MAP; RABGAPLP; RUTBC3
UniProt Entry Name
SGSM3_HUMAN
NCBI Protein Information
small G protein signaling modulator 3; rabGAPLP; OTTHUMP00000199241; merlin binding protein; RUN and SH3 containing 3; merlin-associated protein; RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; rab-GTPase-activating protein-like protein; small G protein signaling modulator 3 protein

UniProt Comments for SGSM3

SGSM3: May play a cooperative role in NF2-mediated growth suppression of cells. Belongs to the small G protein signaling modulator family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 22q13.1-q13.2

Cellular Component: cytosol

Molecular Function: protein binding; Rab GTPase binding

Biological Process: regulation of Rab protein signal transduction; plasma membrane to endosome transport; cell cycle arrest; Rap protein signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-SGSM3 antibody

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