Rabbit Anti-ZMIZ2 Polyclonal Antibody – Cat# MBS623538

ZMIZ2 Antibody – Rabbit Polyclonal

Name: ZMIZ2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS623538
Price: 800 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623538

PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway.… More details

$800 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ZMIZ2, Polyclonal Antibody

Full Product Name

ZMIZ2, CT (PIASz1, Zinc Finger MIZ Domain-containing Protein 2, PIAS-like Protein Zimp7, HRIHFB2007, KIAA1886, ZIMP7)

Product Gene Name

anti-ZMIZ2 antibody

Product Synonym Names

Anti -ZMIZ2, CT (PIASz1, Zinc Finger MIZ Domain-containing Protein 2, PIAS-like Protein Zimp7, HRIHFB2007, KIAA1886, ZIMP7)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes human ZMIZ2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

96,537 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (44788530..44809480). Location: 7p13

OMIM

611196

3D Structure

ModBase 3D Structure for Q8NF64

Immunogen

Synthetic peptide selected from the C-terminal region of human PIASz1 (KLH).

Product Categories/Family for anti-ZMIZ2 antibody

Antibodies; Abs to Transcription Factors

Applications Tested/Suitable for anti-ZMIZ2 antibody

ELISA (EL/EIA), Immunohistochemistry (IHC)

Application Notes for anti-ZMIZ2 antibody

Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100

Other Notes

Small volumes of anti-ZMIZ2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZMIZ2 purchase

MBS623538 is an antibody targeting ZMIZ2. Also known as ZMIZ2, CT (PIASz1, Zinc Finger MIZ Domain-containing Protein 2, PIAS-like Protein Zimp7, HRIHFB2007, KIAA1886, ZIMP7). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZMIZ2. It may not necessarily be applicable to this product.

NCBI GI #

54607110

NCBI GeneID

83637

NCBI Accession #

NP_777589.2

UniProt Primary Accession #

Q8NF64

UniProt Secondary Accession #

O94790; Q0VGB4; Q659A8; Q6JKL5; Q8WTX8; Q96Q01; Q9BQH7; A4D2K7; D3DVL1

UniProt Related Accession #

Q8NF64; Q96HV3

GenBank Nucleotide #

NM_174929.2

NCBI Official Full Name

zinc finger MIZ domain-containing protein 2 isoform 2

NCBI Official Synonym Full Names

zinc finger, MIZ-type containing 2

NCBI Official Symbol

ZMIZ2

NCBI Official Synonym Symbols

NET27; ZIMP7; hZIMP7; KIAA1886; TRAFIP20; DKFZp761I2123

UniProt Protein Name

Zinc finger MIZ domain-containing protein 2

UniProt Synonym Protein Names

PIAS-like protein Zimp7

Protein Family

Zinc finger MIZ domain-containing protein

UniProt Gene Name

ZMIZ2

UniProt Synonym Gene Names

KIAA1886; ZIMP7

UniProt Entry Name

ZMIZ2_HUMAN

NCBI Protein Information

zinc finger MIZ domain-containing protein 2; OTTHUMP00000208713; OTTHUMP00000208714; OTTHUMP00000208715; OTTHUMP00000208716; PIAS-like protein Zimp7

NCBI Summary for ZMIZ2

ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM]

UniProt Comments for ZMIZ2

ZIMP7: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleoplasm; mitochondrion; nuclear replication fork; nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter

Research Articles on ZMIZ2

1. there is an interaction between Zimp7 and PIAS proteins with higher preference for PIAS3, in androgen receptor-mediated transcription

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ZMIZ2 antibody

Products by Pathway	Pathway Diagram
Regulation Of Androgen Receptor Activity Pathway antibodies	Regulation Of Androgen Receptor Activity Pathway Diagram

Diseases associated with anti-ZMIZ2 antibody

Disease Name	Pubmed Publications
Translocation, Genetic Antibodies	>1 publications with ZMIZ2 and Translocation, Genetic

Organs/Tissues associated with anti-ZMIZ2 antibody

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>2 publications with ZMIZ2 and Heart
Testis Antibodies	>1 publications with ZMIZ2 and Testis
Eye Antibodies	>1 publications with ZMIZ2 and Eye
Ovary Antibodies	>1 publications with ZMIZ2 and Ovary
Prostate Antibodies	>1 publications with ZMIZ2 and Prostate
Brain Antibodies	>1 publications with ZMIZ2 and Brain