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BMP2K Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS623594

BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
BIKE (BMP2K), Polyclonal Antibody
Full Product Name
BIKE, ID (BMP-2 inducible Protein Kinase, BMP2K, HRIHFB2017)
Product Gene Name
Product Synonym Names
Anti -BIKE, ID (BMP-2 inducible Protein Kinase, BMP2K, HRIHFB2017)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human BIKE. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
129,172 Da
Chromosome Location
Chromosome: 4; NC_000004.11 (79697532..79837519). Location: 4q21.21
3D Structure
ModBase 3D Structure for Q9NSY1
Immunogen
Synthetic peptide selected from the center region of human BIKE (KLH).
Applications Tested/Suitable for anti-BMP2K antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-BMP2K antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-BMP2K antibody

The anti-Bike C-term Pab is used in Western blot to detect Bike in mouse liver tissue lysate.
Rabbit Anti-BMP2K Polyclonal Antibody – Cat# MBS623594

Immunohistochemistry (IHC) of anti-BMP2K antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-BMP2K Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS623594

Other Notes

Small volumes of anti-BMP2K antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMP2K purchase

MBS623594 is an antibody targeting BMP2K. Also known as BIKE, ID (BMP-2 inducible Protein Kinase, BMP2K, HRIHFB2017). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BMP2K. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
BMP-2-inducible protein kinase isoform a
NCBI Official Synonym Full Names
BMP2 inducible kinase
NCBI Official Symbol
BMP2K
NCBI Official Synonym Symbols
BIKE; HRIHFB2017
UniProt Protein Name
BMP-2-inducible protein kinase
UniProt Gene Name
BMP2K
UniProt Synonym Gene Names
BIKE; BIKe
UniProt Entry Name
BMP2K_HUMAN
NCBI Protein Information
BMP-2-inducible protein kinase

NCBI Summary for BMP2K

This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for BMP2K

BIKE: May be involved in osteoblast differentiation. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, Other; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Other group; NAK family

Chromosomal Location of Human Ortholog: 4q21.21

Cellular Component: nucleoplasm

Molecular Function: protein serine/threonine kinase activity; phosphatase regulator activity; ATP binding

Biological Process: regulation of catalytic activity; regulation of bone mineralization; protein amino acid phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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