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USF2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS624065

USF2 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. This protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
USF2, Polyclonal Antibody
Full Product Name
USF2, ID (Upstream Stimulatory Factor 2, Upstream Transcription Factor 2, FOS-interacting Protein, FIP, Major Late Transcription Factor 2, Class B Basic Helix-loop-helix Protein 12, bHLHb12)
Product Gene Name
anti-Usf2 antibody
Product Synonym Names
Anti -USF2, ID (Upstream Stimulatory Factor 2, Upstream Transcription Factor 2, FOS-interacting Protein, FIP, Major Late Transcription Factor 2, Class B Basic Helix-loop-helix Protein 12, bHLHb12)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human USF2. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
36,954 Da
Chromosome Location
Chromosome: 7; NC_000073.5 (31730267..31741822, complement). Location: 7 A2-B1; 7 11.0 cM
3D Structure
ModBase 3D Structure for Q64705
Immunogen
Synthetic peptide selected from the Center region of human USF2 (KLH).

Product Categories/Family for anti-Usf2 antibody

Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-Usf2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Usf2 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-Usf2 antibody

Western blot analysis of USF2 Antibody (Center) in mouse cerebellum tissue lysates (35ug/lane).USF2 (arrow) was detected using the purified Pab.
Rabbit Anti-USF2 Polyclonal Antibody – Cat# MBS624065

Immunohistochemistry (IHC) of anti-Usf2 antibody

USF2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the USF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-USF2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS624065

Other Notes

Small volumes of anti-Usf2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Usf2 purchase

MBS624065 is an antibody targeting Usf2. Also known as USF2, ID (Upstream Stimulatory Factor 2, Upstream Transcription Factor 2, FOS-interacting Protein, FIP, Major Late Transcription Factor 2, Class B Basic Helix-loop-helix Protein 12, bHLHb12). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Usf2. It may not necessarily be applicable to this product.

NCBI GI #
6755945
NCBI GeneID
22282
NCBI Accession #
NP_035810.1
UniProt Primary Accession #
Q64705
UniProt Secondary Accession #
Q3UIL2; Q8VE59
UniProt Related Accession #
Q64705
GenBank Nucleotide #
NM_011680.2
NCBI Official Full Name
upstream stimulatory factor 2
NCBI Official Synonym Full Names
upstream transcription factor 2
NCBI Official Symbol
Usf2
NCBI Official Synonym Symbols
Usf-2; bHLHb12; MGC91056
UniProt Protein Name
Upstream stimulatory factor 2
UniProt Synonym Protein Names
Major late transcription factor 2; Upstream transcription factor 2
Protein Family
Upstream stimulatory factor
UniProt Gene Name
Usf2
UniProt Entry Name
USF2_MOUSE
NCBI Protein Information
upstream stimulatory factor 2; major late transcription factor 2

UniProt Comments for Usf2

USF2: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Cellular Component: nucleoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein dimerization activity; protein binding; protein homodimerization activity; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; double-stranded DNA binding; bHLH transcription factor binding; transcription factor activity

Biological Process: lactation; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; lipid homeostasis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter by glucose
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Research Articles on Usf2

1. USF2 promotes renal renin expression and stimulates angiotensin II generation, leading to activation of the intrarenal renin-angiotensin system.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-Usf2 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >7 publications with Usf2 and Kidney Diseases
 Breast Neoplasms Antibodies  >6 publications with Usf2 and Breast Neoplasms
 Skin Diseases Antibodies  >5 publications with Usf2 and Skin Diseases
 Lung Diseases Antibodies  >4 publications with Usf2 and Lung Diseases
 Cell Transformation, Neoplastic Antibodies  >4 publications with Usf2 and Cell Transformation, Neoplastic
 Prostatic Neoplasms Antibodies  >3 publications with Usf2 and Prostatic Neoplasms
 Adenoma Antibodies  >2 publications with Usf2 and Adenoma
 Lung Neoplasms Antibodies  >2 publications with Usf2 and Lung Neoplasms
 Death Antibodies  >2 publications with Usf2 and Death
 Chromosome Aberrations Antibodies  >2 publications with Usf2 and Chromosome Aberrations

Organs/Tissues associated with anti-Usf2 antibody

 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >33 publications with Usf2 and Other
 Liver Antibodies  >33 publications with Usf2 and Liver
 Blood Antibodies  >19 publications with Usf2 and Blood
 Kidney Antibodies  >14 publications with Usf2 and Kidney
 Brain Antibodies  >11 publications with Usf2 and Brain
 Lung Antibodies  >9 publications with Usf2 and Lung
 Testis Antibodies  >9 publications with Usf2 and Testis
 Ovary Antibodies  >8 publications with Usf2 and Ovary
 Pancreas Antibodies  >7 publications with Usf2 and Pancreas
 Intestine Antibodies  >4 publications with Usf2 and Intestine
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