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Protein Kinase C (PKC) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS624261

The Protein Kinase C (PKC) family of homologous serine/threonine protein kinases is involved in a number of processes such as growth, differentiation, and cytokine secretion. At least eleven isozymes have been described. PKC consists of a single polypeptide… More details

$755 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Protein Kinase C (Pkc), Polyclonal Antibody
Full Product Name
Protein Kinase C, phosphorylated (Ser-657/Tyr-658) (PKC)
Product Gene Name
anti-Pkc antibody
Product Synonym Names
Anti -Protein Kinase C, phosphorylated (Ser-657/Tyr-658) (PKC)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rabbit, Rat
Form/Format
Supplied as a liquid in PBS, 50% glycerol, 1mg/ml BSA, and 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Detects an 82kD protein corresponding to the molecular mass of phoshorylated PKCa on SDS-PAGE immunoblots of neonatal rat brain lysate. Similar results were seen in other PKCa-expressing cells, such as human SKN-SH, endothelial, and HeLa cells, as well as rabbit spleen fibroblasts and rat pituitary cells. In immunoprecipitation experiments with various PKC isoforms, this antibody detected PKCa and PKCb, but not other PKC isoforms in rat brain lysate.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Chromosome Location
Chromosome: LG11; NC_007080.3 (13974235..13992933, complement)
Immunogen
Phospho-PKCa (Ser-657/Tyr-658) synthetic phosphopeptide (coupled to carrier protein) corresponding to amino acid residues around serine 657 and tyrosine 658 of human PKCa. This sequence is similar to a dual phosphorylation site found in PKCbI (Ser-661/Tyr-662). These human sequences are highly conserved in rat and mouse PKCa and PKCbI. In addition, this dual site is homologous to threonine 674 and tyrosine 675 in human PKCg, although this reactivity has not been confirmed.

Product Categories/Family for anti-Pkc antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-Pkc antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Pkc antibody
Suitable for use in ELISA, Western Blot or for antigen applications in immunological protocols.

Other Notes

Small volumes of anti-Pkc antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pkc purchase

MBS624261 is an antibody targeting Pkc. Also known as Protein Kinase C, phosphorylated (Ser-657/Tyr-658) (PKC). Reactive in Human, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Pkc. It may not necessarily be applicable to this product.

NCBI GI #
201023355
NCBI GeneID
406106
NCBI Accession #
NP_001128420.1
GenBank Nucleotide #
NM_001134948.1
NCBI Official Full Name
protein kinase C
NCBI Official Synonym Full Names
protein kinase C
NCBI Official Symbol
Pkc
Protein Family
Protein kinase C and casein kinase II substrate protein
NCBI Protein Information
protein kinase C

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Pkc antibody

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 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram

Organs/Tissues associated with anti-Pkc antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Pkc and Bone
 Connective Tissue Antibodies  >4 publications with Pkc and Connective Tissue
 Heart Antibodies  >3 publications with Pkc and Heart
 Muscle Antibodies  >3 publications with Pkc and Muscle
 Brain Antibodies  >3 publications with Pkc and Brain
 Vascular Antibodies  >2 publications with Pkc and Vascular
 Embryonic Tissue Antibodies  >2 publications with Pkc and Embryonic Tissue
 Ear Antibodies  >1 publications with Pkc and Ear
 Kidney Antibodies  >1 publications with Pkc and Kidney
 Umbilical Cord Antibodies  >1 publications with Pkc and Umbilical Cord
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