• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Connexin 43 (CX43) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6242705

MBS6242705 is an antibody targeting Cx43. Also known as Connexin 43 (Cx43, Gap Junction Alpha 1 Protein, CxA-1) (Biotin). Reactive in Canine, Human, Mouse, Porcine, Rat. Host: Mouse. More details

$1335 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Connexin 43 (Cx43), Monoclonal Antibody
Full Product Name
Connexin 43 (Cx43, Gap Junction Alpha 1 Protein, CxA-1) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2Q250
Host
Mouse
Species Reactivity
Canine, Human, Mouse, Porcine, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography
Specificity
Recognizes mouse Connexin 43, Mr 43-47kD. Species Crossreactivity: porcine, rat, human and canine. Species Sequence Homology: bovine. No known homology with other connexins.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
43,004 Da
3D Structure
ModBase 3D Structure for P23242
Immunogen
Synthetic peptide corresponding to aa252-270 at the C-terminal of the mouse connexin 43 sequence.
Conjugate
Biotin
Applications Tested/Suitable for anti-Cx43 antibody
ELISA (EIA), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB)

Western Blot (WB) of anti-Cx43 antibody

Western Blot Analysis: Rat brain lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-Connexin 43. Arrow indicates protein Connexin 43 (~43kD) using C7857.
Mouse Anti-CX43 Monoclonal Antibody – Cat# MBS6242705

Western Blot (WB) of anti-Cx43 antibody

Western Blot Analysis: Respresentative image from a previous lot. Mouse brain (Lane1) and rat brain (Lane2) were resolved by electrophoresis transfered and probed with C7857. Arrow indicates protein Connexin 43 (~43kD).
Mouse Anti-CX43 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6242705

Product References and Citations for anti-Cx43 antibody

1. Tansey, Erin E, et al. (2006). Ann. Thorac. Surg. 82: 1472-1479. 2. Arita, Ken, et al. (2006). Am. J. Pathol. 169: 416-423.

Other Notes

Small volumes of anti-Cx43 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Cx43. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
connexin 43
NCBI Official Synonym Full Names
gap junction protein, alpha 1
NCBI Official Symbol
Gja1
NCBI Official Synonym Symbols
Cx43; Npm1; Cnx43; Gja-1; AU042049; AW546267; Cx43alpha1; connexin43
UniProt Protein Name
Gap junction alpha-1 protein
UniProt Synonym Protein Names
Connexin-43; Cx43; Gap junction 43 kDa heart protein
UniProt Gene Name
Gja1
UniProt Synonym Gene Names
Cxn-43; Cx43
NCBI Protein Information
gap junction alpha-1 protein

UniProt Comments for Cx43

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization (PubMed:15181016). Plays an essential role in gap junction communication in the ventricles (PubMed:26403541).
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000