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Connexin 45 (CX45) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6242707

MBS6242707 is an antibody targeting CX45. Also known as Connexin 45 (GJC1, Gap Junction protein, gamma 1, 45kD, Cx45, CX45, DKFZp686P0738, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7) (Biotin). Reactive in Human, Rat. Host: Mouse. More details

$1335 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Connexin 45 (CX45), Monoclonal Antibody
Full Product Name
Connexin 45 (GJC1, Gap Junction protein, gamma 1, 45kD, Cx45, CX45, DKFZp686P0738, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2Q266
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human Connexin 45. Species Crossreactivity: rat.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
45,470 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (42875816..42908179, complement). Location: 17q21.31
OMIM
608655
3D Structure
ModBase 3D Structure for P36383
Immunogen
Synthetic peptide corresponding to aa354-367 of human connexin 45, H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu- Cys-OH, conjugated to KLH. Species Sequence Homology: canine; 100% and mouse; 92%.
Conjugate
Biotin
Applications Tested/Suitable for anti-CX45 antibody
Immunocytochemistry (ICC), Western Blot (WB)

Testing Data of anti-CX45 antibody

Staining of Cx45 transfected rat C6 cells.
Mouse Anti-CX45 Monoclonal Antibody – Cat# MBS6242707

Other Notes

Small volumes of anti-CX45 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CX45. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gap junction gamma-1 protein
NCBI Official Synonym Full Names
gap junction protein, gamma 1, 45kDa
NCBI Official Symbol
GJC1
NCBI Official Synonym Symbols
CX45; GJA7
UniProt Protein Name
Gap junction gamma-1 protein
UniProt Synonym Protein Names
Connexin-45; Cx45; Gap junction alpha-7 protein
UniProt Gene Name
GJC1
UniProt Synonym Gene Names
GJA7; Cx45
UniProt Entry Name
CXG1_HUMAN
NCBI Protein Information
gap junction gamma-1 protein; connexin 45; connexin-45; gap junction alpha-7 protein

NCBI Summary for CX45

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for CX45

GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: connexon complex; endoplasmic reticulum membrane; plasma membrane; gap junction; integral to membrane

Molecular Function: ion channel activity; gap junction channel activity

Biological Process: cardiac muscle development; synaptic transmission; intercellular junction assembly; visual perception; muscle contraction; gap junction assembly; transport; vasculogenesis; cell development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CX45 antibody

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