UBE2Q2 Antibody – Rabbit Polyclonal

The ubiquitination pathway is known to regulate critical control points in multiple cellular processes by targeting proteins for activation, degradation, or localization at specific intracellular sites. The pathway involves an enzymatic cascade in which the first step activates ubiquitin by forming a high energy thiolester intermediate to ubiquitin activating enzyme (E1) that is subsequently transferred to members of an E2 ubiquitin conjugating enzyme superfamily. The E2 ubiquitin conjugating 45 enzymes function together with a larger superfamily of E3 ubiquitin ligases to transfer activated ubiquitin to specific cellular proteins. The existence of E2 and E3 superfamilies reflects the specificity of each E2-E3 cognate pair for a specific group of cellular substrates. UBE2Q2 is a potentially unique member of the ubiquitin conjugating enzyme superfamily that includes at least 17 phenotypically different subfamilies, many of which contain isozymes.

Small volumes of anti-UBE2Q2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS624307 is an antibody targeting UBE2Q2. Also known as UBE2Q2 (Ubiquitin-conjugating Enzyme E2 Q2, Ubiquitin Carrier Protein Q2, Ubiquitin-protein Ligase Q2). Reactive in Human. Host: Rabbit.