• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

VGLUT2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6244665

MBS6244665 is an antibody targeting VGLUT2. Also known as VGLUT2 (Vesicular Glutamate Transporter 2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent Inorganic Phosphate Cotransporter, Solute Carrier Family 17 Member 6, Slc17a6,… More details

$1375 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VGLUT2, Monoclonal Antibody
Full Product Name
VGLUT2 (Vesicular Glutamate Transporter 2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent Inorganic Phosphate Cotransporter, Solute Carrier Family 17 Member 6, Slc17a6, Dnpi) (PE)
Product Gene Name
anti-VGLUT2 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
13A229
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes rat VGLUT2. Species Crossreactivity: human
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Molecular Weight
64,576 Da
3D Structure
ModBase 3D Structure for Q9JI12
Immunogen
Recombinant protein corresponding to rat VGLUT2. Species sequence homology: mouse.
Conjugate
PE

Product Categories/Family for anti-VGLUT2 antibody

Antibodies; Transport Proteins
Applications Tested/Suitable for anti-VGLUT2 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Testing Data of anti-VGLUT2 antibody

Mouse VGLUT2
Mouse Anti-VGLUT2 Monoclonal Antibody – Cat# MBS6244665

Testing Data of anti-VGLUT2 antibody

staining of rat Habenula floating brain tissue.
Mouse Anti-VGLUT2 Monoclonal Antibody, Testing Data – Cat# MBS6244665

Product References and Citations for anti-VGLUT2 antibody

1. Barnes JA, Ebner BA, Duvick LA, Gao W, Chen G, Orr HT, Ebner TJ (2011) The Journal of neuroscience : the official journal of the Society for Neuroscience.31:12778-89. 2. Gomez-Nieto R, Rubio ME (2011) Neuroscience.179:188-207. Epub 2011 Feb 1. 3. Peiyan Wong, Jon H Kaas, Peiyan Wong, Jon H Kaas (2009) Brain, behavior and evolution.73:206-28 4.Tetsushi Sadakata, Wataru Kakegawa, Akira Mizoguchi, Miwa Washida, Ritsuko Katoh-Semba, Fumihiro Shutoh, Takehito Okamoto, Hisako Nakashima, Kazushi Kimura, Mika Tanaka, Yukiko Sekine, Shigeyoshi Itohara, Michisuke Yuzaki, Soichi Nagao, Teiichi Furuichi (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience.27:2472-825. Hrabovszky, Erik, et al. (2006) Endocrinology, 147: 3818-25 (2006)Localization and osmotic regulation of vesicular glutamate transporter-2 in magnocellular neurons of the rat hypothalamus Lrabovszky, E. et al. (2006) Neurochem. Int., Epub: (2006).

Other Notes

Small volumes of anti-VGLUT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VGLUT2. It may not necessarily be applicable to this product.

NCBI GI #
16758166
NCBI GeneID
84487
NCBI Accession #
NP_445879.1
UniProt Primary Accession #
Q9JI12
UniProt Related Accession #
Q9JI12
GenBank Nucleotide #
NM_020346.1
NCBI Official Full Name
vesicular glutamate transporter 2
NCBI Official Synonym Full Names
solute carrier family 17 (vesicular glutamate transporter), member 6
NCBI Official Symbol
Slc17a6
NCBI Official Synonym Symbols
Dnpi; Vglut2
UniProt Protein Name
Vesicular glutamate transporter 2
UniProt Synonym Protein Names
Differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 6
Protein Family
Vesicular glutamate transporter
UniProt Gene Name
Slc17a6
UniProt Synonym Gene Names
Dnpi; Vglut2; VGluT2
UniProt Entry Name
VGLU2_RAT
NCBI Protein Information
vesicular glutamate transporter 2; differentiation-associated BNPI; solute carrier family 17 member 6; differentation-associated Na-dependent inorganic phosphate cotransporter; differentiation-associated Na(+)-dependent inorganic phosphate cotransporter;

NCBI Summary for VGLUT2

Na+-dependent inorganic phosphate cotransporter; involved in Ca2+-dependent glutamate release from astrocytes [RGD, Feb 2006]

UniProt Comments for VGLUT2

SLC17A6: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: synaptic vesicle; neuron projection; synaptic vesicle membrane; early endosome; integral to membrane; cell junction

Molecular Function: symporter activity; L-glutamate transmembrane transporter activity

Biological Process: sodium ion transport; neurotransmitter uptake
Show more

Research Articles on VGLUT2

1. The results indicate that glutamatergic Vsp neurons sending their axons to the thalamic regions express VGLUT2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VGLUT2 antibody

 Reference Product  PubMed Publications
 Calb2 antibody  >4 publications with VGLUT2 and Calb2
 Slc32a1 antibody  >3 publications with VGLUT2 and Slc32a1
 Gad1 antibody  >3 publications with VGLUT2 and Gad1
 Sst antibody  >1 publications with VGLUT2 and Sst
 Calb1 antibody  >1 publications with VGLUT2 and Calb1
 Syp antibody  >1 publications with VGLUT2 and Syp

Pathways associated with anti-VGLUT2 antibody

 Products by Pathway  Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Nicotine Addiction Pathway antibodies  Nicotine Addiction Pathway Diagram
 Nicotine Addiction Pathway antibodies  Nicotine Addiction Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram

Diseases associated with anti-VGLUT2 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >44 publications with VGLUT2 and Nervous System Diseases
 Pain Antibodies  >23 publications with VGLUT2 and Pain
 Brain Diseases Antibodies  >20 publications with VGLUT2 and Brain Diseases
 Movement Disorders Antibodies  >9 publications with VGLUT2 and Movement Disorders
 Nerve Degeneration Antibodies  >8 publications with VGLUT2 and Nerve Degeneration
 Epilepsy Antibodies  >5 publications with VGLUT2 and Epilepsy
 Hypotension Antibodies  >4 publications with VGLUT2 and Hypotension
 Ataxia Antibodies  >4 publications with VGLUT2 and Ataxia
 Seizures Antibodies  >3 publications with VGLUT2 and Seizures
 Inflammation Antibodies  >3 publications with VGLUT2 and Inflammation

Organs/Tissues associated with anti-VGLUT2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >290 publications with VGLUT2 and Brain
 Eye Antibodies  >16 publications with VGLUT2 and Eye
 Dorsal Root Ganglion Antibodies  >9 publications with VGLUT2 and Dorsal Root Ganglion
 Inner Ear Antibodies  >3 publications with VGLUT2 and Inner Ear
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000