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NR1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6244738

MBS6244738 is an antibody targeting NR1. Also known as NR1, CT (NMDA (N-methyl-D-aspartate) Receptor subunit NR1) (MaxLight 405). Reactive in Rat. Host: Mouse. More details

$1290 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NR1, Monoclonal Antibody
Full Product Name
NR1, CT (NMDA (N-methyl-D-aspartate) Receptor subunit NR1) (MaxLight 405)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG
Clone Number
0.T.190
Host
Mouse
Species Reactivity
Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by protein G affinity chromatography from ascites.
Specificity
Recognizes rat NR1 (Mr 130kD). An additional band (Mr 200kD) may be detected at higher concentrations. The epitope maps to a region (aa834-864) common to all NR1 isoforms and so should crossreact with all NR1 isoforms.
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Molecular Weight
101,987 Da
3D Structure
ModBase 3D Structure for P35439
Immunogen
His tag fusion protein corresponding to aa834-938 of rat NR1. Peptide sequence homology: human and mouse, 100%
Conjugate
MaxLight405

Product Categories/Family for anti-NR1 antibody

Applications Tested/Suitable for anti-NR1 antibody
Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)

Testing Data of anti-NR1 antibody

Rat brain microsome extract probed with N5380-05 (0.5ug/ml).
Mouse Anti-NR1 Monoclonal Antibody – Cat# MBS6244738

Product References and Citations for anti-NR1 antibody

1. Hisatsune, C., et al., J. Biol. Chem. 272: 20805-20810, 1997. 2. Leonard, A.S. and J.W. Hell, J. Biol. Chem. 272: 12107-12115, 1997. 3. Raymond, L.A., et al., J. Physiol. Paris. 88: 181-192, 1994. 4. Tingley, W.G., et al., Nature 364: 70-73, 1993.5. Tingley, W.G., et al., J. Biol. Chem. 272: 5157-5166, 1997. 6. Molinuevo, J.L., et al. (2005) Am. J. Alzheimers Dis. Other Demen. 20: 77-85. 7. Popescu, G., and Auerbach, A. (2004). Neuroscientist. 210: 192-198.

Other Notes

Small volumes of anti-NR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 1 isoform 1b
NCBI Official Synonym Full Names
glutamate ionotropic receptor NMDA type subunit 1
NCBI Official Symbol
Grin1
NCBI Official Synonym Symbols
NR1; GluN1; NMDAR1
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 1
UniProt Synonym Protein Names
Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1
Protein Family
UniProt Gene Name
Grin1
UniProt Synonym Gene Names
Nmdar1; GluN1; NMD-R1
NCBI Protein Information
glutamate receptor ionotropic, NMDA 1

NCBI Summary for NR1

subunit of NMDA-preferring ionotropic glutamate receptors; may play a role in long term potentiation [RGD, Feb 2006]

UniProt Comments for NR1

NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NR1 antibody

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