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NRBP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS624903

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in… More details

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Product Overview

Online Datasheet in PDF
Product Name
NRBP (NRBP1), Polyclonal Antibody
Full Product Name
NRBP, NT (Nuclear Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein Kinase, Multiple Domain Putative Nuclear Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, MLF1 Adapter Molecule, MADM)
Product Gene Name
anti-NRBP1 antibody
Product Synonym Names
Anti -NRBP, NT (Nuclear Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein Kinase, Multiple Domain Putative Nuclear Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, MLF1 Adapter Molecule, MADM)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human NRBP. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
59,845 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (27651473..27665126). Location: 2p23
OMIM
606010
3D Structure
ModBase 3D Structure for Q9UHY1
Immunogen
Synthetic peptide selected from the N-terminal region of human NRBP (KLH).

Product Categories/Family for anti-NRBP1 antibody

Antibodies; Abs to Nuclear Proteins
Applications Tested/Suitable for anti-NRBP1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NRBP1 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-NRBP1 antibody

Western blot analysis of anti-NRBP Pab in HL-60 cell lysate (Lane 1) and mouse brain tissue lysate (Lane 2). NRBP (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Rabbit Anti-NRBP1 Polyclonal Antibody – Cat# MBS624903

Immunohistochemistry (IHC) of anti-NRBP1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-NRBP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS624903

Other Notes

Small volumes of anti-NRBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NRBP1 purchase

MBS624903 is an antibody targeting NRBP1. Also known as NRBP, NT (Nuclear Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein Kinase, Multiple Domain Putative Nuclear Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, MLF1 Adapter Molecule, MADM). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NRBP1. It may not necessarily be applicable to this product.

NCBI GI #
7019333
NCBI GeneID
29959
NCBI Accession #
NP_037524.1
UniProt Primary Accession #
Q9UHY1
UniProt Secondary Accession #
Q53FZ5; Q96SU3; B3KV40; D6W558
UniProt Related Accession #
Q9UHY1
GenBank Nucleotide #
NM_013392.2
NCBI Official Full Name
nuclear receptor-binding protein
NCBI Official Synonym Full Names
nuclear receptor binding protein 1
NCBI Official Symbol
NRBP1
NCBI Official Synonym Symbols
MADM; NRBP; BCON3; MUDPNP; FLJ27109; FLJ35541
UniProt Protein Name
Nuclear receptor-binding protein
Protein Family
Nuclear receptor-binding protein
UniProt Gene Name
NRBP1
UniProt Synonym Gene Names
BCON3; NRBP
UniProt Entry Name
NRBP_HUMAN
NCBI Protein Information
nuclear receptor-binding protein; OTTHUMP00000123427; OTTHUMP00000123428; OTTHUMP00000200794; multiple domain putative nuclear protein; myeloid leukemia factor 1 adaptor molecule

UniProt Comments for NRBP1

NRBP1: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Kinase, protein; Other group; NRBP family

Chromosomal Location of Human Ortholog: 2p23

Cellular Component: nucleoplasm; membrane; perinuclear region of cytoplasm; lamellipodium; endomembrane system; cell cortex

Molecular Function: protein binding; protein homodimerization activity; ATP binding; protein kinase activity

Biological Process: transcription initiation from RNA polymerase II promoter; ER to Golgi vesicle-mediated transport; gene expression; protein amino acid phosphorylation
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Research Articles on NRBP1

1. NS3 protein of dengue virus type 2 interacted specifically with nuclear receptor binding protein, a host cellular protein that influences trafficking between the endoplasmic reticulum and Golgi, and that interacts with Rac3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NRBP1 antibody

 Reference Product  PubMed Publications
 RAC3 antibody  >2 publications with NRBP1 and RAC3
 MLF1 antibody  >2 publications with NRBP1 and MLF1

Pathways associated with anti-NRBP1 antibody

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram

Diseases associated with anti-NRBP1 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with NRBP1 and Kidney Diseases
 Leukemia Antibodies  >1 publications with NRBP1 and Leukemia

Organs/Tissues associated with anti-NRBP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with NRBP1 and Kidney
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