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CD16 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6249525

MBS6249525 is an antibody targeting CD16. Also known as CD16 (FcRIII) (FITC). Reactive in Bovine, Human, Sheep. Host: Mouse. More details

$1040 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD16, Monoclonal Antibody
Full Product Name
CD16 (FcRIII) (FITC)
Product Gene Name
anti-CD16 antibody
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
KD1
Host
Mouse
Species Reactivity
Bovine, Human, Sheep
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Specificity
Recognizes human CD16. Species Crossreactivity: bovine, sheep. Reacts weakly with equine and porcine. Does not react with canine and rat.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
28,050 Da
3D Structure
ModBase 3D Structure for P79107
Immunogen
A polyclonal population of NK cells
Conjugate
FITC

Product Categories/Family for anti-CD16 antibody

Antibodies; CD Markers
Applications Tested/Suitable for anti-CD16 antibody
Flow Cytometry (FC/FACS), Neutralization

Testing Data of anti-CD16 antibody

Human peripheral blood lymphocytes stained with 214585 followed by Rabbit F(ab')2 anti Mouse IgG:FITC.
Mouse Anti-CD16 Monoclonal Antibody – Cat# MBS6249525

Testing Data of anti-CD16 antibody

Human peripheral blood lymphocytes stained with Mouse anti Human CD16: FITC (214586)
Mouse Anti-CD16 Monoclonal Antibody, Testing Data – Cat# MBS6249525

Flow Cytometry (FC/FACS) of anti-CD16 antibody

Flow Cytometric analysis for the evaluation of CD16 expression on bovine monocytes using FITC conjugated Mouse anti Human CD16 antibody (214586).
Mouse Anti-CD16 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6249525

Product References and Citations for anti-CD16 antibody

1. Elhmouzi-Younes, J. et al (2010) Vet. Res. 41:04 2. Ciccone, E. et al (1990) J. Exp. Med. 172:47-52 3. Boysen, P. et al. (2008). Dev Comp Immunol. 32: 773-83. 4. Moretta, A. et al (1989). Int J. Cancer 44:727-730 5. Hernandez-Caselles, T. et al. (2006). J Leukoc Biol. 79: 46-58. 6. Zocchi, M.R. et al. (1998) J Immunol. 161: 2938-43. 7. Connelley, T. et al. (2011). Vet Res. 42: 37. 8. Canton, G.J. et al. (2013) Vet Res. 44: 60. 9. Pomeroy, B. et al. (2016) Longitudinal characterization of bovine monocyte-derived dendritic cells from mid-gestation into subsequent lactation reveals nadir in phenotypic maturation and macrophage-like cytokine profile in late gestation. J Reprod Immunol. 118: 1-8. 10. Pomeroy, B. et al. (2017) Counts of bovine monocyte subsets prior to calving are predictive for postpartum occurrence of mastitis nd metritis. Vet Res. 48 (1): 13. 11. Gibson, A.J. et al. (2016) Differential macrophage function in Brown Swiss and Holstein Friesian cattle. Vet Immunol Immunopathol. 181: 15-23.

Other Notes

Small volumes of anti-CD16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD16. It may not necessarily be applicable to this product.

NCBI GI #
7994573
NCBI GeneID
281766
NCBI Accession #
P79107.1
UniProt Primary Accession #
P79107
UniProt Secondary Accession #
P08637; O75015
UniProt Related Accession #
P79107
NCBI Official Full Name
Low affinity immunoglobulin gamma Fc region receptor III
NCBI Official Symbol
FCGR3A
NCBI Official Synonym Symbols
CD16; FCGR3; FCGR3@
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor III
UniProt Synonym Protein Names
Fc-gamma RIII; FcRIII; CD_antigen: CD16
Protein Family
CD160 antigen
UniProt Gene Name
FCGR3
UniProt Synonym Gene Names
FCGRIII; IgG Fc receptor III; FcRIII
UniProt Entry Name
FCGR3_BOVIN
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor III

UniProt Comments for CD16

Is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Also mediates antibody-dependent cellular toxicity ().

Research Articles on CD16

1. cytotoxic role of lymph node residing NK cells, beyond the predominantly cytokine-producing role previously inferred from studies on human NK cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD16 antibody

 Reference Product  PubMed Publications
 SYK antibody  >2 publications with CD16 and SYK

Pathways associated with anti-CD16 antibody

 Products by Pathway  Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram

Organs/Tissues associated with anti-CD16 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with CD16 and Liver
 Intestine Antibodies  >1 publications with CD16 and Intestine
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