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MSRB2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625014

MSRB2 catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MSRB2, Polyclonal Antibody
Full Product Name
MSRB2 (Methionine Sulfoxide Reductase B2, Methionine-R-sulfoxide Reductase B2 Mitochondrial, MSRB, CBS1, CBS-1, CGI-131, MGC26104, PILB)
Product Gene Name
Product Synonym Names
Anti -MSRB2 (Methionine Sulfoxide Reductase B2, Methionine-R-sulfoxide Reductase B2 Mitochondrial, MSRB, CBS1, CBS-1, CGI-131, MGC26104, PILB)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human MSRB2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
19,536 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (23384427..23410942). Location: 10p12
OMIM
613782
3D Structure
ModBase 3D Structure for Q9Y3D2
Immunogen
Synthetic peptide selected from the Center region of human MSRB2 (KLH).
Applications Tested/Suitable for anti-MSRB2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MSRB2 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-MSRB2 antibody

Western blot analysis of MSRB2 (arrow) using rabbit polyclonal MSRB2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MSRB2 gene.
Rabbit Anti-MSRB2 Polyclonal Antibody – Cat# MBS625014

Immunohistochemistry (IHC) of anti-MSRB2 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma with MSRB2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-MSRB2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS625014

Flow Cytometry (FC/FACS) of anti-MSRB2 antibody

Flow cytometric analysis of ATDC5 cells using MSRB2 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-MSRB2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS625014

Other Notes

Small volumes of anti-MSRB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSRB2 purchase

MBS625014 is an antibody targeting MSRB2. Also known as MSRB2 (Methionine Sulfoxide Reductase B2, Methionine-R-sulfoxide Reductase B2 Mitochondrial, MSRB, CBS1, CBS-1, CGI-131, MGC26104, PILB). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MSRB2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
methionine sulfoxide reductase B2, isoform CRA_d
NCBI Official Synonym Full Names
methionine sulfoxide reductase B2
NCBI Official Symbol
MSRB2
NCBI Official Synonym Symbols
CBS1; MSRB; PILB; CBS-1; CGI-131; MGC26104
UniProt Protein Name
Methionine-R-sulfoxide reductase B2, mitochondrial
UniProt Gene Name
MSRB2
UniProt Synonym Gene Names
CBS-1; MSRB
UniProt Entry Name
MSRB2_HUMAN
NCBI Protein Information
methionine-R-sulfoxide reductase B2, mitochondrial; OTTHUMP00000019305; pilin-like transcription factor

UniProt Comments for MSRB2

MSRB2: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. Belongs to the MsrB Met sulfoxide reductase family.

Protein type: Transcription factor; EC 1.8.4.-; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 10p12

Cellular Component: mitochondrion

Molecular Function: zinc ion binding; peptide-methionine (R)-S-oxide reductase activity; actin binding; transcription factor activity

Biological Process: protein repair; regulation of transcription, DNA-dependent; actin filament polymerization; response to oxidative stress
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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