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USP16 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625193

This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant… More details

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Product Overview

Online Datasheet in PDF
Product Name
USP16, Polyclonal Antibody
Full Product Name
USP16 (Ubiquitin Specific Protease 16, Ubiquitin Specific-processing Protease 16, Deubiquitinating Enzyme 16, Human Ubiquitin Processing Protease, Ubiquitin Carboxyl-terminal Hydrolase 16, Ubiquitin Thioesterase 16, Ubiquitin-processing Protease UBP-M, UB
Product Gene Name
anti-USP16 antibody
Product Synonym Names
Anti -USP16 (Ubiquitin Specific Protease 16, Ubiquitin Specific-processing Protease 16, Deubiquitinating Enzyme 16, Human Ubiquitin Processing Protease, Ubiquitin Carboxyl-terminal Hydrolase 16, Ubiquitin Thioesterase 16, Ubiquitin-processing Protease UBP-M, UB
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by peptide affinity chromatography.
Specificity
Recognizes USP16. Species sequence homology
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
93,570 Da
Chromosome Location
Chromosome: 21; NC_000021.8 (30396938..30426809). Location: 21q22.11
OMIM
604735
3D Structure
ModBase 3D Structure for Q9Y5T5
Immunogen
Synthetic peptide corresponding to NVEWNICQDCKTDNK, from the internal region of human USP16 (NP_001027582.1; NP_001001992.1).

Product Categories/Family for anti-USP16 antibody

Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-USP16 antibody
ELISA (EL/EIA)
Application Notes for anti-USP16 antibody
Suitable for use in ELISA.
Dilution: Peptide ELISA Titer: 1:32,000

Other Notes

Small volumes of anti-USP16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USP16 purchase

MBS625193 is an antibody targeting USP16. Also known as USP16 (Ubiquitin Specific Protease 16, Ubiquitin Specific-processing Protease 16, Deubiquitinating Enzyme 16, Human Ubiquitin Processing Protease, Ubiquitin Carboxyl-terminal Hydrolase 16, Ubiquitin Thioesterase 16, Ubiquitin-processing Protease UBP-M, UB. Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for USP16. It may not necessarily be applicable to this product.

NCBI GI #
75992941
NCBI GeneID
10600
NCBI Accession #
NP_001027582.1
UniProt Primary Accession #
Q9Y5T5
UniProt Secondary Accession #
Q53GP7; Q53HA0; Q5VKN8; Q8NEL3; Q9H3E6; A8MU43; B3KN13; B4DFV8; B4DY37; D3DSD9
UniProt Related Accession #
Q9Y5T5
GenBank Nucleotide #
NM_001032410.1
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 16 isoform a
NCBI Official Synonym Full Names
ubiquitin specific peptidase 16
NCBI Official Symbol
USP16
NCBI Official Synonym Symbols
UBP-M
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 16
UniProt Synonym Protein Names
Deubiquitinating enzyme 16; Ubiquitin thiolesterase 16; Ubiquitin-processing protease UBP-M; Ubiquitin-specific-processing protease 16
UniProt Gene Name
USP16
UniProt Entry Name
UBP16_HUMAN
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 16; OTTHUMP00000096468; OTTHUMP00000096469; OTTHUMP00000096470; ubiquitin thioesterase 16; deubiquitinating enzyme 16; ubiquitin thiolesterase 16; ubiquitin specific protease 16; ubiquitin-processing protease UBP-M; ubiquitin-specific processing protease 16; ubiquitin-specific-processing protease 16

UniProt Comments for USP16

USP16: a ubiquitous ubiquitin-processing protease that may de-ubiquitinate one or more critical proteins that are involved in the condensation of mitotic chromosomes, possibly acting selectively on histones H2A and H2B, the major ubiquitinated proteins of chromatin. Is phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition.

Protein type: EC 3.4.19.12; Ubiquitin conjugating system; Ubiquitin-specific protease; Protease

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: cytoplasm; nucleus

Molecular Function: ubiquitin binding; zinc ion binding; histone binding; cysteine-type endopeptidase activity; transcription coactivator activity; ubiquitin-specific protease activity

Biological Process: regulation of transcription from RNA polymerase II promoter; mitosis; proteasomal ubiquitin-dependent protein catabolic process; transcription, DNA-dependent; cell division; positive regulation of transcription, DNA-dependent; positive regulation of translational elongation; positive regulation of transcription from RNA polymerase II promoter; cell cycle; response to DNA damage stimulus; protein homotetramerization; histone deubiquitination
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Research Articles on USP16

1. a new cryptic USP16-RUNX1 fusion in chronic myelomonocytic leukemia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-USP16 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >1 publications with USP16 and Adenocarcinoma
 Lung Neoplasms Antibodies  >1 publications with USP16 and Lung Neoplasms
 Leukemia Antibodies  >1 publications with USP16 and Leukemia
 Leukemia, Myeloid Antibodies  >1 publications with USP16 and Leukemia, Myeloid
 Hematologic Diseases Antibodies  >1 publications with USP16 and Hematologic Diseases
 Bone Marrow Diseases Antibodies  >1 publications with USP16 and Bone Marrow Diseases
 Fatty Liver Antibodies  >1 publications with USP16 and Fatty Liver

Organs/Tissues associated with anti-USP16 antibody

 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >1 publications with USP16 and Thyroid
 Lung Antibodies  >1 publications with USP16 and Lung
 Muscle Antibodies  >1 publications with USP16 and Muscle
 Liver Antibodies  >1 publications with USP16 and Liver
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