• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SCYL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS625310

SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. SCYL2 is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SCYL2, Polyclonal Antibody
Full Product Name
SCYL2, CT (SCY1-like Protein 2, Coated Vesicle-associated Kinase of 104kD, CVAK104, KIAA1360)
Product Gene Name
anti-SCYL2 antibody
Product Synonym Names
Anti -SCYL2, CT (SCY1-like Protein 2, Coated Vesicle-associated Kinase of 104kD, CVAK104, KIAA1360)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human SCYL2. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
103,709 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (100661549..100733917). Location: 12q23.1
3D Structure
ModBase 3D Structure for Q6P3W7
Immunogen
Synthetic peptide selected from the C-terminal region of human SCYL2 (KLH).

Product Categories/Family for anti-SCYL2 antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-SCYL2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SCYL2 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:10-1:50

Western Blot (WB) of anti-SCYL2 antibody

Western blot analysis of anti-SCYL2 Pab (AP7024b) in T47D (left) and mouse brain (right) tissue lysates (35ug/lane). SCYL2(arrow) was detected using the purified Pab.
Rabbit Anti-SCYL2 Polyclonal Antibody – Cat# MBS625310

Immunohistochemistry (IHC) of anti-SCYL2 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with SCYL2 (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-SCYL2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS625310

Other Notes

Small volumes of anti-SCYL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCYL2 purchase

MBS625310 is an antibody targeting SCYL2. Also known as SCYL2, CT (SCY1-like Protein 2, Coated Vesicle-associated Kinase of 104kD, CVAK104, KIAA1360). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SCYL2. It may not necessarily be applicable to this product.

NCBI GI #
47604944
NCBI GeneID
55681
NCBI Accession #
NP_060458.3
UniProt Primary Accession #
Q6P3W7
UniProt Secondary Accession #
Q96EF4; Q96ST4; Q9H7V5; Q9NVH3; Q9P2I7; A8KAB5
UniProt Related Accession #
Q6P3W7; Q9NWE9
GenBank Nucleotide #
NM_017988.4
NCBI Official Full Name
SCY1-like protein 2
NCBI Official Synonym Full Names
SCY1-like 2 (S. cerevisiae)
NCBI Official Symbol
SCYL2
NCBI Official Synonym Symbols
CVAK104; FLJ10074; KIAA1360
UniProt Protein Name
SCY1-like protein 2
UniProt Synonym Protein Names
Coated vesicle-associated kinase of 104 kDa
Protein Family
SCY1-like protein
UniProt Gene Name
SCYL2
UniProt Synonym Gene Names
CVAK104; KIAA1360
UniProt Entry Name
SCYL2_HUMAN
NCBI Protein Information
SCY1-like protein 2; coated vesicle-associated kinase of 104 kDa

UniProt Comments for SCYL2

SCYL2: Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system. Belongs to the protein kinase superfamily.

Protein type: Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; SCY1 family

Chromosomal Location of Human Ortholog: 12q23.1

Cellular Component: Golgi apparatus; clathrin-coated vesicle; perinuclear region of cytoplasm; endosome membrane

Molecular Function: protein binding; ATP binding; protein kinase activity; receptor binding

Biological Process: positive regulation of receptor internalization; endosome to lysosome transport; protein amino acid phosphorylation
Show more

Research Articles on SCYL2

1. Studies identify CVAK104 as a novel binding partner of Dishevelled (Dvl) and that CVAK104 also interacts with Fzd5.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SCYL2 antibody

 Disease Name  Pubmed Publications
 Edema Antibodies  >1 publications with SCYL2 and Edema

Organs/Tissues associated with anti-SCYL2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with SCYL2 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000